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Chapter #2
Drug Action & Handling
| Term | Definition |
|---|---|
| Low Dose-Effect Curve | Measuring the response to the dose of the drug. |
| Potency | The amount of drug to produce an effect. |
| Efficacy | Related to the maximal effect of a drug regardless of dose. |
| Therapeutic Action | The intended or desired results. |
| Therapeutic Range | The range between the dose causing the minimum effect and the dose causing the minimum adverse effect. |
| Therapeutic Index (TI) | The number that determines the safety of a drug. (The greater the TI value, the safer the drug) |
| Hepatic | Liver |
| Biotransformation | The body's way of changing a drug so that it can be more easily excreted by the kidneys. |
| Tolerance | The need for an increasingly larger dose of the drug to obtain the same effects of the original dose. |
| Renal | Kidney |
| Duration | The length of a drug's effect. |
| Half-life | The amount of time that passes for its concentration to fall to half (50%) of its original blood level. |