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Chapter 1

Introduction/general principals

TermDefinition
Drug chemicals that act on living systems at the molecular
Pharmacology the study of drugs and their effects on living organisms
Pharmacodynamics the study of the action of drugs on living organisms
Pharmacokinetics the study of what the body does to a drug; the measurement of the absorption, distribution, metabolism, and excretion of drug from the body.
Brand (Trade) Name the manufacturer’s name, written with the first letter capitalized (e.g., Valium, Vazepam, Tylenol).
Generic Name name for the chemical makeup of a drug, written in lowercase, first letter NOT capitalized (e.g., diazepam for Valium or Vazepam, acetaminophen for Tylenol). Generic drugs marketed without brand names are less expensive than brand name drugs.
Contraindications medical or physical conditions that make the drug inadvisable
Synergism getting more than the desired effects when taking two drugs (1+1>2) (e.g., oxycodone + acetaminophen = Percocet)
Tolerance decreased effect of a drug over time with the patient needing larger doses to achieve the same effect.
Toxicology the study of the harmful effects of drugs on living tissues
Therapeutic Effect desired effect of a drugs
Efficacy is the maximum intensity of effect or response that can be produced by a drug
Chemically equivalent when two formulations of a drug meet the chemical and physical standards
Biologically equivalent when two formulations of a drug produce similar concentrations of the drug in the blood and tissues
Therapeutically equivalent When two formulations of a drug prove to have equal therapeutic effects
Orphan drugs drugs developed to specifically treat rare medical conditions
qd (latin) once a day (quaque die)
bid (latin) twice a day (bis in die)
tid (latin) 3 times a day (ter in die)
qid (latin) 4 times a day (quarter in die)
pc (latin) after meals (post cebum)
ac (latin) before meals (ante cebum)
po (latin) by mouth (per os)
prn (latin) as needed (pro re nata)
hs (latin) at bedtime (hora somni)
Therapeutic Classification What is affected by the drug
Pharmacological Classification Broader classification based on the general therapeutic effects or use of the drug. Categorized into various classes based on their effects.
Mechanism Classification Mechanism of action of the drug (specific thing the drug does on the molecular level)
Schedule I Highest abuse potential, no accepted medical use
Schedule II High abuse potential, written prescription with provider signature only, NO REFILLS
Schedule III Moderate abuse potential, prescriptions faxed or electronically, up to 5 refills per 6 months
Schedule IV Less abuse potential, prescriptions faxed or electronically, up to 5 refills per 6 months
Schedule V Least abuse potential, bought over the counter
Created by: tommylai
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