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Pharmacology ch.7&8
terminology
| Question | Answer |
|---|---|
| study of the body's structure | anatomy |
| study of the body's function | physiology |
| spongy substances found in center and creates blood cells | bone marrow |
| place of union between two or more bones of skeleton | joint |
| noncontractile connective tissue, ties bone to bone | ligaments |
| joint surface covered with cartilage | cartilaginous joint |
| joint surface covered by fibrous connective tissue | fibrous joint |
| joint surface covered by fluid-filled, fibrous sac | synovial joint |
| organ that creates movement by contracting | muscle |
| tough cordlike tissue, connects muscle to bone | tendons |
| voluntary muscle contraction, use for locomotion and maintain posture. (striated) | skeletal muscle |
| involuntary muscle contraction | smooth muscle |
| heart muscle found in heart involuntary | cardiac muscle |
| process of constant breakdown and buildup of bones | bone remodeling |
| cell that breakdown bones an releases calcium into the bloodstream | osteoclast |
| cell that takes calcium from bone to build bone tissue | osteblast |
| sensory and motor nerve cells | somatic neurons |
| area of connection between a neuron and muscle fiber | neuromuscular junction |
| condition affecting the joints; inflammation, joint pain | arthritis |
| degenerative joint disease, cartilage joint become thinner less elastic, causing bone to wear; deformed | osteoarthritis |
| chemicals causing inflammation and swelling; elevates pain threshold | prostaglandins |
| autoimmune disorder, immune system destroys synovial membrane of joint; producing inflammation | rheumatoid arthritis |
| nonsteroidal anti inflammatory drugs inhibits prostaglandins synthesis in tissues, preventing pain receptors from becoming more sensitive | NSAIDS |
| disease modifying antirheumatic drugs , agents that can modify disease progression of rheumatoid arthritis | DMARDS |
| targets part of immune system responsible for inflammation and joint damage | biologic response modifiers |
| form of arthritis resulting from the body's improper excretion of uric acid | gouty arthritis |
| neurotransmitter released by somatic neurons | acetylcholine |
| decrease pain and reduce fever | acetaminophen |
| antidote for an acetaminophen overdose; approved for bronchial disease | acetylcysteine |
| NSAID available for rectal suppository | indomethacin |
| protect stomach form nsaid induced ulcers | arthrotec |
| can induce signs and symptoms of nepatotoxicity | diclofenac |
| can cause birth defects , premature birth, abortion | misoprostol |
| formulated with gold, dmard indicated for ra treatment | auranofin |
| depresses bone marrow function increasing infection potential, may not show therapeutic response up to 3 months | azathioprine |
| antimalaria drug, used to treat ra and lupus | hydroxychloroquine |
| chemotherapy drug, used to treat cancers, arthritic conditions and psoriasis | methotrexate |
| newer drug indicated for moderately to sever active ra | rinvoq |
| used to treat acute gout attacks, to reduce frequency of recurrent episodes of gouty arthritis | colchicine |
| used for preventive gout treatment, one f the top 200 drugs dispensed in pharmacy | allopurinol |
| inhibits uric acid production | febuxostat |
| selective estrogen receptor modulator, works as estrogen receptor by mimicking beneficial effects of estrogen on bone density | SERM |
| inhibits osteoclast formations, decreasing bone reabsorption, increasing bone mass strength | denosumab |
| cramp, sudden and involuntary contraction of one or more muscles | muscle spasms |
| reduces/ prevents skeletal muscle contractions and spasms, provide pain relief | muscle relaxant |
| body's response to tissue injury or infection | inflammation |
| discovered and isolated from the bark of the white willow tree; first used for rheumatic fever | salicylates |
| method that involves pretreating the skin with that needles in specific area, used for pain | acupuncture |
| physical manipulation of the spine based on the theory that proper alignment of the body's musculoskeletal structure will enable the body to heal. | chiropractic care |
| dietary supplement taken with glucosamine for hip and knee oa | chondroitin |
| drug supplement used to improve pain and stiffness in oa | glucosamine |
| bark that contains salicin, used to treat many kinds of pain | willow bark |
| breaks into central nervous and peripheral nervous system | autonomical |
| brain and spinal cord that process and evaluate incoming info and determine the responses; coordinates and control activity of other body systrems | central nervous system |
| nerves and sensory receptors, located outside cns, carries neural signals between body and cns | peripheral nervous system |
| sensory division that carries info to the cns detects heat, cols, pain, presences of chemicals | afferent system |
| includes nerves that sense touch, pressure, temperature, painful stimuli, on surface of body ( muscle, joint) | somatic sensory system |
| nerves that sense pain, reflex signals in the internal organs, blood vessels | visceral sensory system |
| motor division that carries info from cns to a parts of the body ( muscles, glands to produce a response) | efferent system |
| regulates motor activity that is involuntary ( cardiac muscles, smooth muscles, glands) | autonomic nervous system |
| regulates motor activity that is voluntary (skeletal muscles) | somatic nervous system |
| transmits info to body from sympathetic ganglion chain in thoracic and lumber regions of spinal cord | sympathetic nervous system |
| transmit info to body from brain and cervical and sacral regions of spinal cord | parasympathetic nervous system |