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Neuro Week 2

QuestionAnswer
levodopa/carbidopa drug information ADRs-dyskiniesia, psychosis, orthostatic hypotension, urine discoloration Contraindications-glaucoma, melanoma, depression Interactions, antipsychotics, protein, vitamin B Admin-oral Intervention-orthostatic vitals Patient Ed-avoid high protein
pramipexole drug information -used for restless lef ADRs-same as other Parkinson, more nausea, sleep attacks Intervention-monitor orthostasis Interactions-Cimetidine and antipsychotics
selegiline drug information Interactions-tyramine and many meds ADR-insomnia
donepezil drug information ADR-bradycardia leading to syncope Patient-caregiver present, take w/ food before bed Interactions-anticholinergics, NSAIDs
memantine drug information ADRs-CNS effects and GI effects Precautions-liver or renal impairment, seizure disorder Interactions-OTC antacids
Interferon information ADRs-flue like symptoms, myelosuppression, immune suppression liver toxicity
sumatriptan drug information ADRs-chest heaviness, bronchospasm, coronary vasospasm Admin-repeated doses with 24 hour max Contraindication-arterial disease Interactions-serotonin syndrome, MAOI
levodopa/carbidopa therapeutic action and pharmacologic action -relieve manifestations of Parkinson's -carbidopa helps levodopa convert to dopamine in brain
pramipexole therapeutic use and pharmacologic action -treat Parkinson's and restless leg syndrome -bind to dopamine receptors
selegiline therapeutic action and pharmacologic action -treat Parkinson's and depression -inhibit monoamine oxidase B
donepezil therapeutic use and pharmacologic action -improve cognitive function in Alzheimer's -prevents acetylcholinesterase from inactivating acetylcholine
memantine therapeutic use and pharmacologic action -treat Alzheimer's (barely works) -block excess glutamate from stimulated NMDA receptors, decreasing influx of calcium into neurons
interferon therapeutic use and pharmacologic action -treat MS -inhibit movement of leukocytes
sumatriptan therapeutic use and pharmacologic action -relieve manifestations of existing migraine -serotonin agonist, reverse 5-HT/CRGP ratio
Created by: mbaldwin13
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