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PPA 3
| Generic Name | Brand Name | Drug Class | Usual Adult Dose (Max) |
|---|---|---|---|
| Acetaminophen 300 mg/Codeine 300 mg | Tylenol #3 | Analgesic, opioid combination | 1-2 tablets q4-6h (max of 4g APAP/day). Limit use to 5 days for acute pain and 3 days for fever |
| Ampicillin/Sulbactam | Unasyn | Antibiotic, penicillin | Combination product formulated in a 2:1 ratio. Dosage recommendations are expressed as total grams of ampicillin/sulbactam. IM, IV: 1-2 g ampicillin as 1.5-3 g Unasyn® q6h |
| Anastrozole | Arimidex | Antineoplastic agent/Aromatase inhibitor | 1 mg PO qD |
| Aspirin | Aspirin | Analgesic, salicylate, antiplatelet | ACS: 162-325 mg LD to 81-325 mg qD MD. Analgesic and antipyretic IR: 325-650 mg prn q4hrs (max dose 4 gm/day). |
| Azelastine | Astepro Nasal | Antihistamine, Histamine (H1) antagonist | 1-2 sprays in each nostril BID or 2 sprays qD |
| Bimatoprost | Lumigan, Latisse | Antiglaucoma, prostaglandin | Instill 1 drop into affected eye(s) every evening |
| Bisoprolol | Zebeta | Antihypertensive/CHF, Beta blocker (B1) | Initial 2.5-5 mg PO (max 20 mg/day) |
| Buprenorphine/Naloxone | Suboxone, Bunavail, Zubsolv | Opioid partial agonist/antagonist | Suboxone: each has different dosing. Sublingual initial: buprenorphine 2mg/naloxone 0.5 mg OR buprenorphine 4mg/naloxone 1 mg. May titrate |
| Carisoprodol | Soma | Skeletal muscle relaxant | 250-350 mg PO TID and at bedtime |
| Cefazolin | Ancef | Antibiotic, 1st generation cephalosporin | Dose depends on condition. IV: 250mg-2g q6-12h |
| Cefepime | Maxipime | Antibiotic, 4th generation cephalosporin | IV: 1-2g q8-12h |
| Cefoxitin | Mefoxin | Antibiotic, 2nd generation cephalosporin | IM, IV: 1-2 g q6-8h |
| Ceftriaxone | Rocephin | Antibiotic, 3rd generation cephalosporin | IM, IV: 1-2g q12-24h |
| Cefuroxime | Zinacef | Antibiotic, 2nd generation cephalosporin | PO: 250-500mg BID IV: 750mg-1.5g q8h |
| Clarithromycin | Biaxin | Antibiotic, macrolide | PO: 250 to 500 mg every 12 hours or 1000 mg (two 500 mg extended-release tablets) once daily |
| Clozapine | Clozaril, FazaClo, Versacloz | Antipsychotic, atypical 2nd generation | PO: 12.5mg daily or BID increased to 300-450 mg/day (max dose 900mg/day) |
| Conjugated Estrogens | Premarin | Hormone replacement, estrogen derivative | PO: 0.3-0.625 mg daily or on a cycle, higher doses can be used for other conditions. IM, IV: 25 mg, may repeat in 6-12 hours if needed or 25 mg IV repeated q4-6h for 24 hour |
| Cyclosporine, ophthlamic | Restasis, Cequa | Immunosuppressant agent, calcineurin inhibitor | 1 drop in both eyes q12h |
| Dabigatran | Pradaxa | Anticoagulant, direct thrombin inhibitor | 150 mg PO BID |
| Darbepoetin | Aranesp | Hepatic agents, coronary stimulating factor erythropoiesis | Individualize dosing and use the lowest dose necessary to reduce the need for red blood cell (RBC) transfusions. SC or IV: 6.25-200 mcg per week based on hemoglobin value |
| Dexamethasone | Decadron | Corticosteroid | PO, IM, IV: 0.5 to 9 mg/day in divided doses q6-12 hours; dose depends upon condition being treated and response of patient |
| Dexlansoprazole | Dexilant | PPI, GI agent | Healing 60 mg PO once daily for up to 8 weeks . Maintenance: PO: 30 mg once daily |
| Dexmedetomidine | Precedex | Sedative, Alpha 2 adrenergic agonist | ICU Sedation IV: 1 mcg/kg over 10 minutes followed by 0.2-0.7 mcg/kg/hr maintenance. Procedural Sedation IV: loading 1 mcg/kg over 10 minutes with 0.6mcg/kg/hour for maintenance |
| Diphenoxylate/Atropine | Lomotril | Gastrointestinal, antidiarrheal | 5mg diphenoxylate component four times per day PO PRN (20mg/day max) |
| Dutasteride | Avodart | 5-alpha reductase inhibitor | 0.5 mg PO qD |
| Edoxaban | Savaysa | Anticoagulant, Factor Xa inhibitor | 60 mg PO qD. Dosage adjustments for renal function, wt <60kg, and patients on p-glycoprotein |
| Emtricitabine/tenofovir alafenamide | Descovy | Antiretroviral Anti-HIV | 1 tablet (emtricitabine 200 mg/tenofovir alafenamide 25 mg) PO qD |
| Enoxaparin | Lovenox | Anticoagulant, low molecular weight heparin (LMWH) | Prophylaxis SC: 30 mg twice daily or 40 mg daily subcutaneously. Treatment SC: 1mg/kg twice daily or 1.5mg/kg daily subcutaneously |
| Epinephrine | EpiPen, Adrenalin, Auvi-Q | Alpha/Beta agonist | IV: 1 mg every 3-5 minutes until return of spontaneous circulation. IM: 0.3 mg followed by one dose if needed for allergic reaction |
| Epoetin | Epogen, Procrit, Retacrit | Hematopoietic agent, colony stimulating factor erythropoiesis | Consider initiating treatment when hemoglobin is less than 10g/dL. IV, SC: Initial dose 50-100 units/kg once weekly |
| Eszopiclone | Lunesta | Hypnotic, non-benzodiazepine | 1-3 mg PO at bedtime (max 3 mg) |
| Etanercept | Enbrel | Antirheumatic; Tumor Necrosis Factor (TNF) Blocking Agent | SC: 50 mg once-twice weekly depending on disease state |
| Evolocumab | Repatha | Antilipemic agent, PCSK9 inhibitor | SC: 140mg every 2 weeks OR 420 mg once monthly |
| Exenatide | Bydureon, Byetta | Antidiabetic, GLP-1 Receptor Agonist | IR SC: 5 mcg twice daily within 60 minutes of eating, maybe increased to 10mcg twice daily. ER SC: 2 mg once weekly |
| Fentanyl | Abstral | Analgesic, Opioid | ΙV: 50 to 100 mcg loading dose with 25- 50mcg/hr titrated to patient need. Transdermal: 25 to 100 mcg/hour |
| Fexofenadine | Allegra | Antihistamine, H1 antagonist | 60 mg PO BID or 180 mg qD |
| Fidaxomicin | Dificid | Antibiotic, macrolide | Clostridioides difficile infection PO: 200 mg twice daily for 10 days |
| Fosphenytoin | Cerebyx | Anticonvulsant | Fosphenytoin 1.5 mg is equivalent to phenytoin 1 mg and is referred to as 1 mg PE. IV: 10-20 mg PE/kg daily as a single dose |
| Gentamicin | Garamycin | Antibiotic, aminoglycoside | Depends on condition. Conventional: IM, IV: 3 to 5 mg/kg/day in divided doses every 8 hours. Once daily (extended interval dosing): IV: 5 to 7 mg/kg/day once daily |
| Glecaprevir and Pibrentasvir | Mavyret | Antihepaciviral, NS3/A4 Protease Inhibitor (Anti-HCV) | Length of treatment depends on genotype and presence of cirrhosis. 3 tablets PO qD |
| Haloperidol | Haldol | Antipsychotic, first generation | Psychosis: 0.5-5 mg PO in divided doses. Schizophrenia: IM: 2-5 mg in divided doses (20 mg/day). |
| Heparin | Heparin | Anticoagulant | Thromboembolism prophylaxis: SC: 5000 units every 8- 12 hours. Treatment of thromboembolism IV: 80 units/kg IV push followed by continuous infusion of 18 units/kg/hour |
| Human NPH Insulin | Humulin N, Novolin N | Insulin, intermediate-acting | 0.4-1 units/kg/day SC (usually twice per day) |
| Humulin Insulin Regular | Humulin R, Novolin R | Insulin, short-acting | 4-6 units of 0.1 unit/kg or 10% basal insulin dose SC administered before the largest meal of the day |
| Hydromorphone | Dilaudid | Analgesic, Opioid | Doses should be titrated to provide adequate pain relief. Parenteral doses up to 5x more potent than oral, NOT equiv ROA. Opiate naïve PO: Initial: 2-4 mg q4-6 hours PRN (tablets) or 2.5-10 mg q3-6h prn (oral solution). IV: 0.2-1 mg q2-3h PRN. |
| Ibandronate | Boniva | Bisphosphonate | PO: 150 mg once monthly. IV: 3mg every 3 months |
| Imipenem/cilastatin | Primaxin | Antibiotic, carbapenem | Depends on infection. IV: 500mg q6h or 1,000mg q8h (max 4,000 mg/day) |
| Insulin glulisine | Apidra | Insulin, rapid-acting | Initial SC: 0.4 to 0.5 units/kg/day; conservative initial doses of 0.2 to 0.4 units/kg/day may be considered to avoid the potential for hypoglycemia. Usual maintenance SC range: 0.4 to 1 units/kg/day in divided doses |
| Ipratropium | Atrovent HFA | COPD, anticholinergic | 2 oral inhalation four times daily (12 inhalations/day) |
| Ipratropium/albuterol | Combivent Respimat | COPD/asthma, bronchodilator (anticholinergic and beta-2 agonist) | COPD Oral Inhalation: 1 inhalation every 6 hours. Asthma Oral inhalation: 2 inhalations every 6 hours |
| Ketamine | Ketalar | Anesthetic, general | IM: 4-10 mg/kg. IV: 0.5-2 mg/kg |
| Lacosamide | Vimpat | Anticonvulsant | For partial onset seizures Initial IV, PO: 100 mg twice daily and up to 150-200 mg twice daily |
| Lactulose | Constulose, Enulose, Generlac, Kristalose | Laxative, Ammonium Detoxicant | Constipation 10-20 g PO per day up to 40g/day |
| Lansoprazole | Prevacid | Gastrointestinal, PPI | 15-30 mg PO qD |
| Levonorgestrel | Plan B | Contraceptive, Progestin | Two-dose regimen: One 0.75 mg tablet PO ASAP within 72 hours of unprotected intercourse; a second tablet should be taken 12 hours after first dose. Single-dose: 1.5 mg tab PO ASAP within 72 hours of unprotected sexual intercourse |
| Lidocaine | Lidoderm, Xylocaine | Anesthetic analgesic, local antiarrhythmic, Class IB | Apply 4.5 mg/kg/day topically in four doses. Apply 5% patch to painful area for 12 hours every day |
| Linezolid | Zyvox | Antibiotic, oxazolidinone | Depends on condition. PO: 400-600 mg q12h IV: 600 mg q12h |
| Loperamide | Imodium | Gastrointestinal, antidiarrheal | 4 mg loading dose PO followed by 2 mg after each loose stool. Up to 16 mg/day |
| Lubiprostone | Amitizia | Gastrointestinal agent, chloride channel activator | Chronic idiopathic constipation: 24 mg PO BID IBS with constipation in females < 18 yo: 8 mcg PO BID Opioid induced constipation: 24 mcg PO BID |
| Lurasidone | Latuda | Antipsychotic, atypical Second generation | Bipolar depression: initial 20 mg PO at bedtime, titrated up to 120mg/day. Schizophrenia: initial 40 mg PO qD increased to 160 mg/day |
| Maraviroc | Selzentry | Antiretroviral: CCR5 Antagonist (Anti-HIV) | 300 mg PO BID |
| Medroxyprogesterone | Depo-Provera, Depo-SubQ, Provera 1-4, Provera (tablets) | Contraceptive, progestin | Contraception: 150 mg IM q3 months. Endometriosis: SC: 104 mg every 3 months. PO: 5-10 mg qD for 5-10 days starting on day 16 or 21 of menstrual cycle |
| Merropenem | Merrem | Antibiotic, carbapenem | 500 mg IV q6h OR 1-2 g q8h |
| Metaxalone | Skelaxin | Skeletal muscle relaxant | 800 mg PO TID-QID |
| Methodone | Dolophine | Analgesic, opioid | Pain management: PO: 2.5 q8h titrated. IV: 2.5-10 mg q8-12h. Detoxification PO: titrate to about 40 mg/day in divided doses to achieve stabilization |
| Metoclopramide | Reglan | Gastrointestinal, prokinetic, antiemetic | PO: 10-20 mg QID. IV: 10-20 mg over 1-2 min |
| Metolazone | Zaroxyolyn | Diuretic, thiazide-like | 2.5-20 mg PO qD |
| Midazolam | Nayzilam, (Nasal) Versed | Benzodiazepine | Pre-op sedation: 0.1-0.35 mg/kg IV over 20-30 sec. Seizures: 5 mg (one nasal spray) as a single dose in one nostril; may repeat in 10 minutes in alternate nose |
| Mometasone | Nasonex, Sinuva Nasal (Implant) | Corticosteroid, nasal | Nasal: 2 sprays in each nostril daily. Sinus implant: 1 implant placed in sinuses every 90 days |
| Moxifloxacin | Moxifloxacin, Avelox (IV) | Antibiotic, fluoroquinolone | PO, IV: 400 mg daily |
| Naloxone | Evzio, Narcan | Opioid antagonist | Opioid overdose IV, IM, SC: 0.4-2 mg repeated every 2 to 3 minutes up to 10 mg. Intranasal: 4 mg (1 spray) as a single dose in one nostril. May repeat in 3 to 5 minutes if respiratory depression persists |
| Nicotine | Nicoderm, Nicorette, Nicotrol | Smoking cessation aid | Gum: chew 1 piece at smoking urge or 4 mg q1-8 hours. Patients who smoke their first cigarette w/in 30 min of waking should use 4 mg; otherwise 2 mg. Lozenge: 2 or 4 mg q1-8 hours. Transdermal: 21 mg/day or 14mg/day titrated down to 7 mg/day over 10 wks |
| Nystatin | Bio-Statin | Antifungal agent | Oral candidasis: suspension: 400,000-600,000 units 4 times/day; swish in the mouth and retain for as long as possible before swallowing |
| Penicillin V Potassium | Pen VK | Antibiotic, penicillin | 125-500 mg PO q6-8 hours |
| Phenazopyridine | Azo, Pyridium | Urinary Analgesic | Rx: 200 mg TID PO after meals for 2 days. OTC: 190 mg PO TID with or after meals up to 2 days |
| Phenobarbital | Phenobarbital | Anticonvulsant | Seizures: oral, IV: 2 mg/kg/day in divided doses up to 20 mg/L steady state level. Status epilepticus: 15 mg/kg IV |
| Phenytoin | Dilantin | Anticonvulsant | PO: usual maintenance dose of 300-600 mg/day. IV: 15-20 mg/kg loading dose (max 2 g) |
| Piperacillin/tazobactam | Zosyn | Antibiotic, penicillin | Adult doses are expressed as the combined amount of piperacillin and tazobactam. IV: 3.375 gm q6h or 4.5gm q6-8h (max 18 gm/day) |
| Prasugrel | Effient | Antiplatelet agent | 60 mg PO LD within 1 hour of PCI then 5-10 mg daily |
| Prochlorperazine | Compro (rectal); Compazine (oral) | Antipsychotic, first generation; antiemetic | Nausea and vomiting: 5-10 mg TID-QID (max 40 mg/day). IV: 2.5-10 mg TID-QID Rectal: 25 mg BID |
| Propofol | Diprivan | Anesthetic, general | Initial IV: 5 mcg/kg/min (or 0.3 mg/kg/hr); increase by 5 to 10 mcg/kg/min (or 0.3 to 0.6 mg/kg/hr) every 5 to 10 min until desired sedation level is achieved; usual maintenance: 5 to 50 mcg/kg/min (or 0.3 to 3 mg/kg/hr). |
| Raloxifene | Evista | Selective estrogen receptor modulator (SERM) | 60 mg PO qD Patients should receive supplemental calcium and vitamin D if dietary intake is inadequate |
| Raltegravir | Isentress | Antiretroviral integrase inhibitor (Anti-HIV) | Treatment naïve patients PO: 400 mg twice daily or 1200 mg once daily. Treatment experienced patients PO: 400 mg twice daily |
| Ramelteon | Rozerem | Sedative/hypnotic, melatonin receptor agonist | 8 mg PO within 30 minutes of bedtime |
| Ranolazine | Ranexa | Antianginal agent | 500 mg PO BID initially up to 1000 mg BID |
| Rifaximin | Xifaxan | Antibiotic, rifamycin | Hepatic encephalopathy PO: 550 mg twice per day. Irritable bowel syndrome— diarrhea. PO: 550 mg three times per day for 14 days. Traveler’s Diarrhea PO: 200 mg three times per day for 3 days |
| Sacubitril/valsartan | Entresto | CHF, ARB with a neprilysin inhibitor | PO: 24/26 mg, 49/51 mg, 97/103 mg twice daily |
| Saxagliptin | Onglyza | Antidiabetic, dpp-4 inhibitor | 2.5-5 mg PO qD |
| Sildenafil | Viagra, Revatio | Phosphodiesterase-5-enzyme inhibitor | Erectile dysfunction 50 mg PO q hour prior to sexual activity. Pulmonary HTN (revatio): 5-10 mg PO TID (4-6 hours apart), 20 mg TID |
| Solifenacin | Vesicare | Anticholinergic agent | 5 mg/day PO up to 10 mg/day |
| Tacrolimus | Prograf, Astagraf XL, Envarsus XR | Immunosuppressant agent, calcineurin inhibitor | IR PO: 0.1-0.15 mg/kg/day in 2 divided doses. ER PO: 0.1-0.2 mg/kg daily |
| Tadalafil | Cialis | Phosphodiesterase-5-enzyme inhibitor | Erectile Dysfunction PO: PRN dosing 10 mg at least 30 minutes prior to sexual activity. Pulmonary Arterial Hypertension PO: 40mg once daily |
| Terbinafine | Terbinafine | Antifungal agent | 250 mg PO daily, duration of treatment depends on condition, usually 6-12 weeks |
| Ticagrelor | Brillinta | Antiplatelet agent | 180 mg PO LD + 90 mg PO BID maintenance dose |
| Tobramycin | Tobradex | Antibiotics, aminoglycoside | Conventional: 1 to 2.5 mg/kg/dose every 8 to 12 hours; to ensure adequate peak concentrations early in therapy. Once-daily: 4 to 7 mg/kg/dose once daily |
| Tolterodine | Detrol LA | Anticholinergic, overactive bladder | IR PO: 2 mg twice daily; dose may be lowered to 1 mg twice daily based on individual response. ER capsule PO: 4 mg once daily; dose may be lowered to 2 mg once daily |
| Torsemide | Demadex | Diuretic, loop | CHF 10-20 mg PO daily (200 mg). IV: 10-20 mg initial dose (100-200 mg single dose) |
| Valproic Acid and Derivatives (Divalproex sodium, valproate sodium) | Depakote, Depakene, Depacon (IV) | Anticonvulsant (histone deacetylase inhibitor) | Seizures PO: 10 to 15 mg/kg/day initial dose up to 60 mg/kg/day in divided doses. IV: Total daily IV dose should be equivalent to the total daily oral valproate dose (expressed as valproic acid) and divided every 6 hours |
| Vancomycin | Vancocin, Firvanq | Antibiotic, glycopeptide | IV: 15 to 20 mg/kg/dose (rounded to the nearest 250 mg; usual maximum: 2 g/dose initially) every 8 to 12 hours. PO: 125 to 500 mg 4 times daily. Oral is ineffective for treating systemic infections due to lack of absorption |
| Varenicline | Chantix | Smoking cessation aid | Days 1-3: PO: 0.5 mg daily. Days 4-7: PO: 0.5 mg twice daily. Maintenance (week 2- 12) PO: 1 mg twice daily |