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HEENT
HEAD, EARS, EYES, NOSE, THROAT
| Pharmacologic Category | Generic Name | Brand Name | Common Indications | Key Side Effects | Other Notes | Contraindications | US Boxed Warning |
|---|---|---|---|---|---|---|---|
| Alpha2 agonist | brimonidine (ophthalmic) | Alphagan P | Elevated IOP | ocular hypersensitivity, drowsiness, allergic conjunctivitis, conjunctival hyperemia, ocular pruritus | CI with MAOI therapy | ||
| Non-selective beta-blocker | timolol (ophthalmic) | Timoptic, Timoptic XE | Elevated IOP | ocular stinging and burning | |||
| Non-selective beta-blocker | timolol (ophthalmic) | Istalol | Elevated IOP | ocular stinging and burning | |||
| Prostaglandin analog | bimatoprost (ophthalmic) | Lumigan, Latisse | Elevated IOP, eyelash hypotrichosis | eyelash growth, conjunctival hyperemia, ocular pruritus, iris color change, periocular hyperpigmentation | |||
| Prostaglandin analog | latanoprost (ophthalmic) | Xalatan | Elevated IOP | eyelash growth, conjunctival hyperemia, ocular pruritus, iris color change, periocular hyperpigmentation | |||
| Prostaglandin analog | travoprost (ophthalmic) | Travatan Z | Elevated IOP | eyelash growth, conjunctival hyperemia, ocular pruritus, iris color change, periocular hyperpigmentation | |||
| Calcineurin inhibitor | cyclosporine (ophthalmic) | Restasis | Keratoconjunctivitis sicca | ocular burning, stinging, pruritus, foreign body sensation, hypersensitivity reaction | |||
| Corticosteroid | prednisolone (ophthalmic) | Pred Forte, Pred Mild, Omnipred | Ophthalmic inflammation | glaucoma, cataract formation, corneal thinning, secondary infection | |||
| Pediculocide | permethrin (topical) * | Nix, Elimite | Lice, scabies | itching, redness, swelling of scalp | |||
| Retinoic acid derivative | adapalene (topical) * | Differin | Acne | xeroderma, skin exfoliation, erythema, stinging, burning | |||
| Antiseptic | chlorhexidine (topical, PO) | Hibiclens, Peridex | Skin cleanser, periodontitis, gingivitis | dysgeusia, increased tartar formation, mouth discoloration, mouth irritation | |||
| Corticosteroid | clobetasol (topical) | Temovate, Clobex | Psoriasis, atopic dermatitis | burning of skin, dryness of skin, hypopigmentation, secondary infection | do not use for > 2 weeks because it may cause adrenal suppression | ||
| Corticosteroid | triamcinolone (topical) | Kenalog | Psoriasis, atopic dermatitis | burning of skin, dryness of skin, hypopigmentation, secondary infection | do not use for > 2 weeks because it may cause adrenal suppression | ||
| Alpha (α1) agonist | pseudoephedrine (PO) * | Sudafed | Nasal congestion | Increased blood pressure, tachycardia, insomnia, restlessness | Sold behind the counter | ||
| Corticosteroid | fluticasone (intranasal) * | Flonase | Allergic rhinitis | nasal dryness, epistaxis, nasal burning, headache | |||
| Corticosteroid | triamcinolone (intranasal) * | Nasacort | Allergic rhinitis | nasal dryness, epistaxis, nasal burning, headache | |||
| Histamine (H1) blocker | azelastine (intranasal) * | Astepro | Allergic rhinitis | headache, nasal dryness, epistaxis, bitter taste | |||
| Histamine (H1) blocker | diphenhydramine (PO *, IV) | Benadryl | Allergic rhinitis, allergic reaction, insomnia | drowsiness, constipation, xerostomia, urinary retention | |||
| Histamine (H1) blocker | hydroxyzine (PO, IV) | Atarax, Vistaril | Pruritis, nausea, anxiety | dizziness, somnolence, xerostomia, blurred vision, QTc prolongation | |||
| Histamine (H1) blocker | cetirizine (PO) * | Zyrtec | Allergic rhinitis | drowsiness, dizziness, headache | |||
| Histamine (H1) blocker | loratadine (PO) * | Claritin | Allergic rhinitis | drowsiness, dizziness, headache | |||
| Histamine (H1) blocker | fexofenadine (PO) * | Allegra | Allergic rhinitis | drowsiness, dizziness, headache | |||
| Histamine (H1) blocker | olopatadine (ophthalmic) * | Pataday, Patanol | Allergic conjunctivitis | ocular burning, discomfort, dryness | |||
| Histamine (H1) blocker and opioid analgesic | promethazine and codeine (PO) | Phenergan with Codeine | Cough, cold | dizziness, somnolence, xerostomia, blurred vision, constipation, respiratory depression (dose-related) | opioid-containing cough and cold products no longer indicated for use in patients <18 years of age | concomitant use of opioids with benzodiazepines or other CNS depressants (including alcohol), may result in profound sedation, respiratory depression, coma, and death | |
| Opioid analgesic and expectorant | codeine and guaifenesin (PO) | Robitussin AC, Cheratussin AC | Cough, cold | dizziness, somnolence, constipation, respiratory depression (dose-related) | opioid-containing cough and cold products no longer indicated for use in patients <18 years of age | ||
| Antitussive | dextromethorphan (PO) * | Delsym | Cough | nausea, drowsiness, dizziness, constipation | |||
| Antitussive | benzonatate (PO) | Tessalon Perles | Cough | sedation, nasal congestion, chills, chest numbness, bronchospasm | do not break capsule because it may cause choking |