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Ch.13

Drug-to-Food Interactions

TermDefinition
What are 3 ways that food affects how medications work in the body? -Slow digestion -Alter the pH of the stomach -Change the bacterial flora of the intestines
What does "take on an empty stomach" mean? Take medications 2 hours after food was last ingested
Why are antacids, PPI's, and H2 Agonists taken on an empty stomach? Food is also an antacid so it will render the medication ineffective
Why should fluoroquinolones not be taken with dairy products? Dairy products can bind to the medication and make it ineffecticve
Why are NSAID's usually taken with food? Because they can irritate the stomach lining
What happens when you take anticholinergic medications with alcohol? Increased sedation
What is the effect of having alcohol with disulfiram? Severe nausea and vomiting due to decreased ability to digest alcohol
What are medications with similar effects as disulfiram when taken with alcohol? -Cephalosporins -Chloral hydrate -Metronidazole
Why should patients limit alcohol consumption when taking tylenol? Increased risk of liver damage
What about grapefruit juice makes it interact with so many medications? It's a CYP450 inhibitor so it increases the level of medication metabolized by CYP450
Created by: Learning=Earning
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