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Ch. 13

Drug Interact

TermDefinition
How are drug-to-drug interactions managed? By increasing or decreasing the dose of one of the medications
How do pharmacokinetic drug interactions occur? One med. effects the ADME process of another
How do pharmacodynamic interactions occur? One med. adds to or neutralizes the other med.'s effect without affecting the pharmacokinetics of the other medication
What is a substrate? A substrate is a med. that is metabolized by an enzyme
What is the effect of a med. that is a CYP450 inducer? Increased metabolism, decreased bioavailability
What is the effect of a med. that is a CYP450 Inhibitor? Decreased metabolism, increased bioavailability
What is the effect of protein displacement? Increased levels of active medication
Amoxicillin-Clavulanic acid, a combo. antibiotic, is an example of which type of drug-to-drug interaction? Synergistic
What is an example of antagonism that is beneficial to patients? An antidote to a poison
Which type of drug-to-drug interaction are caused by taking two med.s of the same drug class? A duplication
Created by: Learning=Earning
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