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Ch.13

Pharmacokinetics

TermDefinition
What are the 4 processes studied in pharmacokinetics? (ADME)Absorption, Distribution, Metabolism, and Excretion
Absorption of a medication is dependent on which 2 processes? -Disintegration: The breaking down of meds into smaller parts -Dissolution: Dissolving a solid med. into a liquid
What is a DISADVANTAGE of a sustained release product? The preparation might now release enough medication to treat severe symptoms, such as breakthrough pain
Which 3 factors effect the distribution of a medication? -Acid-Base Status -Solubility -Volume of distribution
What are 5 examples of medications that are weak bases? -Morphine -Diphenhydramine -Diazepam -Amlodipine -Midazolam
Endings of med. names that indicate weak bases? -acetate, -calcium, -decanoate, -disodium, -dinitrate, -furoate, -mononitrate, and -propionate
What type of molecule dissolves in water? A charged molecule that is highly polar
Which conditions are treated by medications with a high volume of distribution? Illnesses that originate in the brain
What is first-pass metabolism? When a med. is first destroyed by the liver before it enters the excretory system
What is the primary organ of excretion for water soluble medications? The kidneys
Created by: Learning=Earning
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