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Quiz 5
Top 200 Drugs
| Generic | Brand | Class | Indication | AE | Pearls |
|---|---|---|---|---|---|
| Buspirone | BuSpar | antianxiety agent | GAD | akathisia, SS, dizziness, nervousness, drowsiness | Option if desire no sexual SEs, onset delayed by 2-4 wks w/full effects in 3-6 wks |
| Citalopram | Celexa | SSRI | MDD | QT prolongation, SS, increased bleeding risk, sexual dysfunction, insomnia | Monitor for other QT prolongation meds, no full effect til 4-6 wks |
| Desvenlafaxine | Pristiq | SNRI | MDD | HTN, SS, increased bleeding risk, dizziness, drowsiness | NOT for CVD, active metabolite of venlafaxine |
| Duloxetine | Cymbalta | SNRI | MDD, GAD, fibromyalgia, musculoskeletal pain, neuropathic pain | increased bleeding risk, SS, weight loss, insomnia, severe skin rxns | NOT for CVD, higher doses for fibro |
| Escitalopram | Lexapro | SSRI | MDD, GAD | QT prolongation, SS, increased bleeding risk, sexual dysfunction, insomnia | Option if desire no sexual SEs, S-enantiomer of citalopram, no full effect til 4-6 wk |
| Fluoxetine | Prozac | SSRI | bulimia nerviso, MDD, OCD, PD, bipolar I disorder | QT prolongation, SS, increased bleeding risk, sexual dysfunction, insomnia | Longest t1/2 makes adherence hard, lmany CYP450 DDIs, no full effect til 4-6 wks |
| Levothyroxine | Synthroid, Levoxyl, Levothroid | hormone/thyroid | hypothyroidism | weight loss, sweating, hyperthyroidism, decreased bone mineral density (BMD), CV events | Take 30-60 min on empty stomach b4 food, avoid taking cations w/in 4 hrs |
| Paroxetine | Paxil (XR), Pexeva | SSRI | MDD, GAD, OCD, PD, PTSD, PMD | SJS, TENS, SS, abnormal ejaculation, constipation | Most anticholinergic effects, avoid in elderly & pregnant women, no full effect til 4-6 wks |
| Sertraline | Zoloft | SSRI | MDD, PD, OCD, PTSD, SAD | QT prolongation, SS, increased bleeding risk, sexual dysfunction, insomnia | Edu on many GI SEs, no full effect til 4-6 wks |
| Trazodone | Desyrel | antidepressant, SRI | MDD | priapism, SS, arrythmias, blurred vision, nausea | Usually sleep aid, dose for antidepressive effects too sedating |
| Venlafaxine | Effexor (XR) | SNRI | GAD, MDD, PD, SAD | HTN, SS, increased bleeding risk, dizziness, insomnia | SNRI at high doses, SSRI at low doses, NOT for CVD |
| Vortioxetine | Trintellix | SSRI | MDD | hyponatremia, SS, hypersensitivity rxn, constipation, nausea | Non-selective = many SEs |