Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Herbal Therapy
Selected Herb-Drug Interactions
| Herbal Ingredient Common Name | Documented Drug Interaction | Potential Drug Interaction |
|---|---|---|
| Alfalfa (Medicago sativa) | AnticoagulantsOral contraceptives(⇓ Drug effect) | |
| Angelica root (Angelica sp) | warfarin ⇑ Drug effect | |
| Arnica flower (Arnica montana) | warfarin ⇑ Drug effect | |
| Astragalus (Astragalus membranaceus) | cyclophosphamide ⇓ Drug effect | |
| Betel nut (Areca catechu) | fluphenazine ⇑ Drug toxicity | |
| Bilberry (Vaccinium myrtillus) | Anticoagulants ⇑ Drug effect Antidiabetics ⇑ Drug effect | |
| Black cohosh (Cimicifuga racemosa) | Antihypertensives ⇑ Drug effect digoxin ⇑ Drug absorption Iron salts ⇓ Drug absorption | |
| Bladderwrack (Fucus vesiculosus) | lithium ⇑ Drug effect thyroxine ⇑ Drug effect | |
| Boldo (Peumus boldus) | warfarin ⇑ Drug effect | |
| Cascara (Rhamnus purshiana) | Corticosteroids ⇑ Hypokalemia digoxin ⇑ Drug effect | |
| Cat's claw (Uncaria tomentosa) | cyclosporine ⇑ Drug effect Protease inhibitors ⇑ Drug effect | |
| Cayenne (Capsicum annuum) | theophylline ⇑ Drug absorption | Antiplatelets ⇑ Drug effect |
| Chamomile (Matricaria chamomilla) | Sedatives ⇑ Drug effect simvastatin ⇑ Drug effect warfarin ⇑ Drug effect | |
| Chasteberry (Vitex agnus-castus) | Prolactin inhibitors ⇑ Drug effect | |
| Cocoa (Theobroma cacao) | Antidiabetics ⇓ Drug effect | |
| Cranberry (Vaccinium macrocarpon) | warfarin ⇑ Drug effect | |
| Dandelion (Taraxacum officinale) | Antidiabetics ⇑ Drug effect Diuretics ⇑ Drug effect lithium ⇑ Drug levels | |
| Danshen (Salvia bowelyana; Saliva miltorrhiza) | warfarin ⇑ Drug effect | Antiplatelets ⇑ Drug effect |
| Devil's claw (Harpago-phytum procumbens) | warfarin ⇑ Drug effect | Antiplatelets ⇑ Drug effect |
| Dong quai (Angelica sinensis) | warfarin ⇑ Drug effect | Antiplatelets ⇑ Drug effect |
| Echinacea (Echinacea spp.) | Immunomodulators Altered drug effect Protease inhibitors ⇑ Drug effect | |
| Elder (Sambucus nigra) | Antidiabetics ⇑ Drug effect | |
| Evening primrose (Oenothera biennis) | Anticoagulants ⇑ Drug effect Antiplatelets ⇑ Drug effect phenothiazines ⇑ Seizure risk | |
| Fennel (Foeniculum vulgare) | fluoroquinolones ⇓ Drug absorption | |
| Fenugreek (Trigonella sp.) | warfarin ⇑ Drug effect | Iron ⇓ Drug absorption |
| Feverfew (Tanacetum parthenium) | Antiplatelets ⇑ Drug effect | |
| Flaxseed (Linum usitatissium) | warfarin ⇑ Drug effect | |
| Garcinia (Garcinia cambogia) | warfarin ⇓ Drug effect | |
| Garlic (Allium sativum) | Protease inhibitors ⇓ Drug levels warfarin ⇑ Drug effect | Anticoagulants ⇑ Drug effect Antidiabetics ⇑ Drug effect Antiplatelets ⇑ Drug effect cyclosporine ⇑ Drug effect Non-nucleoside RTIs ⇑ Drug effect |
| Ginger (Zingiber officinale) | phenprocoumon ⇑ Bleeding risk | Anticoagulants ⇑ Drug effect Antiplatelets ⇑ Drug effect |
| Ginkgo (Ginkgo biloba) | trazodone ⇑ Drug effect Antiplatelet agents ⇑ Bleeding risk nifedipine ⇑ Drug effect omeprazole ⇑ Drug effect | Anticoagulants ⇑ Drug effect Antiepileptics ⇓ Drug effect cyclosporine ⇓ Drug absorption Ca++ channel blockers ⇓ Drug effect MAO inhibitors ⇑ Drug effect |
| Ginseng (Panax ginseng, Panax quin-quefolia) | warfarin ⇓ Drug effect phenelzine ⇑ Drug effect | Anticoagulants Altered drug effect Antidiabetics ⇑ Drug effect Antiplatelets Altered drug effect Immunomodulators Altered drug effect MAO inhibitors ⇑ Drug effect |
| Goldenseal (Hydrastis canadensis) | Anticoagulants ⇓ Drug effect Antihypertensives ⇓ Drug effect Immunomodulators Altered drug effect | |
| Green tea (Camellia sinensis) | warfarin ⇓ Drug effect | |
| Guggul (Commiphora mukul) | Anticoagulants ⇑ Drug effect Antiplatelets ⇑ Drug effect diltiazem ⇓ Drug effect | |
| Hawthorn (Crataegus laevigata) | CNS depressants ⇑ Drug effect Antiarrhythmics Altered drug effect digoxin ⇑ Drug effect | |
| Hibiscus (Hibiscus sabdarifa) | chloroquine ⇓ Drug absorption | |
| Juniper (Juniperus communis) | Antidiabetics ⇓ Drug effect Diuretics ⇑ Drug effect lithium ⇑ Drug levels | |
| Kava (Piper methysticum) | alprazolam ⇑ Drug effect levodopa ⇓ Drug effect | Antiepileptics ⇑ Drug effect CNS depressants ⇑ Drug effect |
| Lemon balm (Melissa officinalis) | CNS depressants ⇑ Drug effect | |
| Licorice (Glycyrrhiza glabra) | spironolactone ⇓ Drug effect | Antihypertensives ⇓ Drug effect Antiplatelets ⇑ Drug effect Corticosteroids ⇑ Drug effect digoxin ⇑ Drug effect Diuretics ⇑ Hypokalemia |
| Meadowsweet (Filipendula ulmaria) | warfarin ⇑ Drug effect | |
| Milk thistle (Silybum marianum) | indinavir ⇓ Drug concentration | CYP3A substrate Altered drug effect |
| Oleander (Nerium oleander) | digoxin ⇑ Drug effect | |
| Papaya (Carica papaya) | warfarin ⇑ Drug effect | |
| Passionflower (Passiflora incarnate) | Antiepileptics ⇑ Drug effect CNS depressants ⇑ Drug effect warfarin ⇑ Drug effect | |
| Peppermint (Mentha piperita) | Iron salts ⇓ Drug absorption | |
| Psyllium (Plantago spp.) | Lithium ⇓ Drug absorption | digoxin ⇓ Drug effect |
| Red clover (Trifolium pretense) | warfarin ⇑ Drug effect | |
| Rosemary (Rosmarinus officinalis) | Antidiabetics ⇓ Drug effect | |
| Saw Palmetto (Serenoa repens) | Hormone therapy ⇓ Drug effect warfarin ⇑ Drug effect | |
| Senna (Cassia senna) | Corticosteroids ⇑ Hypokalemia digoxin ⇑ Drug effect | |
| Soy (Glycine max) | warfarin ⇓ Drug effect | |
| Uva ursi (Arctostaphylos uva ursi) | Iron ⇓ Drug absorption | |
| Valerian (Valeriana officinalis) | Barbiturates ⇑ Drug effect | Antiepileptics ⇑ Drug effect CNS depressants ⇑ Drug effect |
| Willow bark (Salix spp.) | warfarin ⇑ Drug effect | |
| Yohimbe (Pausinystalia yohimbe) | Antihypertensives ⇓ Drug effect MAO inhibitors ⇑ Hypertension | |
| St. John's wort (Hypericum perforatum) | alprazolam ⇓ Drug effect;amitriptyline ⇓ Drug level & effect;cyclosporine, digoxin ⇓ Drug level & effect;imatinib, indinavir ⇓ Drug level & effect;irinotecan, midazolam ⇓ Drug level; nifedipine, Oral contraceptives ⇓ Drug level & effect | amiodarone ⇓ Drug level & effect; amsacrine, carbamazepine ⇓ Drug effect; diltiazem ⇓ Drug level & effect; etoposide, omeprazole ⇓ Drug level & effect; |
| St. John's wort (Hypericum perforatum) | SSRIs ⇓ Drug levels; imvastatin ⇓ Drug level; tacrolimus ⇓ Drug level; talinolol ⇓ Drug effect; theophylline, warfarin- Serotonin syndrome, ⇓ Drug level & effect | Triptans ⇓ Drug effect; verapamil Other CYP3A4 or P-gp substrate ⇑ Photosensitivity risk , ⇓ Drug level & effect, Serotonin syndrome |
| Aloe (Aloe vera) | Antidiabetics ⇑ Drug effect; Antiplatelets ⇑ Drug effect ; digoxin ⇑ Drug effect ; Diuretics ⇑ Hypokalemia |
Created by:
zoranrula@yahoo.com
Popular Pharmacology sets