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AIDS Drugs Part I

N(s)RTI/N(t)RTI/NNRTI

QuestionAnswer
Abacavir Ziagen (NsRTI)-No renal dosing and uses alcohol dehyrdogenase
Didanosine Videx (NsRTI)-pancreatitis, renal, peripheral neuropathy, lactic acidosis (CI- tetracyclines, stavudine), if buffered tab it has aspirin
Emtricitabine Emtriva (NsRTI)-nonenteric coated didanosine
Lamivudine Epivir (NsRTI)-Periperal neuropathy, ok Hepatitis infection, room temperature
Stavudine Zerit (NsRTI)-Peripheral neuropathy, lipodystropy, worsens lipids, thymidine analot, refrigerated-Avoid AZT
Zalcitabine Hivid (NsRTI)-peripheral neuropathy, rash, stomatis/oral ulcers, pancreatitis
Zidovudine Retrovir (NsRTI)-macrocyctic anemia (increase MCV), thymidine analogue, low dose EPO/GCSF for anemias
Lamivudine/Zidovudine Combivir (NsRTI)
Abacavir/Lamivudine/Zidovudine Trizivir
Abacavir/Lamivudine Epizicome (HLA-B hypersenstivity reaction to Abacavir
Efavirenz/Emtricitabine/TNF Atripla
Tenofovir Viread (TNF)-NtRTI-hep. B infections, reanal toxicity/failure, BMD, osteoporosis
Tenofovir/emtricitabine Truvada (NtRTI)-fanconi's syndrome
Efavirenz Sustive-NNsRTI-avoid with high fat meals, insomnia, psychosis, dec. AUC substrates, false positive marijuana on urine tox screens.
Etravirine Intelence-NNsRTI-NNRTI resistance approval
Nevirapine Viramune-NNsRTI-SJS/TEN/hepatotoxicity (1st 4 weeks), antihistamines for rash, CI:severe hepatic impairment.
Created by: Alexia4
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