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Cardiac Meds
Unit 6
| Cardiac Meds | Mechanism of Action | Drug Effects/Therapeutic Use | Side Effects | Interactions | Nursing Implications | Classification |
|---|---|---|---|---|---|---|
| Vasotec (enalapril) Zestril (lisinopril) Lotensin (benazepril) Capoten (captopril) Altace (remipril) Accupril (quinapril) | Blocks conversion of AT I --AT II decreases aldosterone which decreases sodium and water reabsorption | decreased constriction leading to decreased resistance and decreased afterload and BP Therapeutic: decrease BP, afterload reduction for CHF, MI Renal Protection with DM | Dry, nonproductive cough Dizziness headache fatigue mood changes loss of taste, proteinuria increase K rash, puritis, anemia | NSAIDS decrease therapeutic effect K sparing diuretics lead to increase K other antihypertensives and diuretics lead to hypotension | Monitor B/P. I/O, daily weights Monitor K levels Focus assessment: cardiac and pulmonsry Education: risk of hypotension, symptoms of hypotension, medication, | ACE-I = pril |
| Cozzar (losartan) atacand (candesartan) Diovan (valsartan) Micardis (telmisartan) | Blocks binding of ATII to its receptors | Vasodilation decreased resistance Therapeutic Use: Decrease BP Tx for CHF Second line for pt. intolerant of ACE-I | Upper respiratory infections headache dizziness, sleep disturbances, diarrhea, dyspnea, heartburn, nasal congestin, back pain and fatigue | Cimetidine (tagament) Increases ARB effect Lithium Increased lithium concentrations Phenobarbital and rifampin decrease ARB effect diuretics enhance hypotensive effects | Monito BP, I/O, daily weight Assess serum K, renal function Focus assessment - cardiac and pulmonsry Patient education - medication, hypotension symptoms | ARB = sartan |
| Inderal (propranolol) Lopressor (metoprolol) Tenormin (atenolol) Coreg (carvedilol) Normodyne (labetolol) | Binds and blocks B1 receptors on hearts conduction system CARDIOSELECTIVE Decreases O2 requirements of myocardial cells by supressing heart activity (MI protective) | decrease HR and BP Increase CO due to increase diastolic time and ventricular fill time decreases renin release Therapeutic: decrease BP, antianginal, cardioprotective | Bradycardia, heart block, heart failure, dizziness, fatigue, lethargy, depression, drowsiness, unusual dreams, brochospasms, impotence | Enhance effect of digoxin and lidocaiine Diuretics enhance hypotensive effect | Monitor B/P, I/O, daily weight Continuous EKG required when IV Focus assessment cardiac and pulmonary contraindicated with bradycardia, heart block, heart failure and some lung diseases | Beta Blocker = lol |