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Pain, Hem, Onc
Pain, Hematology & Oncology
| Generic Name | Brand Name | Pharmacologic Category | Common Indications | Essential Knowledge |
|---|---|---|---|---|
| Fentanyl | Transdermal: Duragesic IV: Sublimaze | Opioid analgesic | Pain | Side Effects: Dizziness, Drowsiness, Itching, N/V, Constipation, Respiratory depression US BW: Risk of addiction, Abuse may lead to OD and death, Abrupt discontinuation may result in withdrawals, Do not use with benzos & CNS depressants |
| Hydromorphone | Dilaudid | Opioid analgesic | Pain | Side Effects: Dizziness, Drowsiness, Itching, N/V, Constipation, Respiratory depression US BW: Risk of addiction, Abuse may lead to OD and death, Abrupt discontinuation may result in withdrawals, Do not use with benzos & CNS depressants |
| Morphine | MS Contin, Kadian | Opioid analgesic | Pain | Side Effects: Dizziness, Drowsiness, Itching, N/V, Constipation, Respiratory depression US BW: Risk of addiction, Abuse may lead to OD and death, Abrupt discontinuation may result in withdrawals, Do not use with benzos & CNS depressants |
| Oxycodone | Oxycontin, Roxicodone | Opioid analgesic | Pain | Side Effects: Dizziness, Drowsiness, Itching, N/V, Constipation, Respiratory depression US BW: Risk of addiction, Abuse may lead to OD and death, Abrupt discontinuation may result in withdrawals, Do not use with benzos & CNS depressants |
| Methadone | Dolophine | Opioid analgesic | Opioid use, Severe chronic pain | Side Effects: Dizziness, Drowsiness, N/V, Constipation, Respiratory depression US BW: QTc interval prolongation and serious arrhythmia have occured during treatment |
| Acetaminophen | PO/PR: Tylenol IV: Ofirmev | Analgesic, antipyretic | Pain, Fever | Side Effects: N/V, Increased hepatic transaminases US BW: Total daily dose from all sources should not exceed max daily limit; Hepatotoxicity |
| Tramadol | Ultram | Central analgesic, Partial opioid agonist | Pain | Side Effects: Dizziness, Drowsiness, N/V, Constipation, Respiratory depression US BW: Serious or fatal respiratory depression Other notes: Lowers seizure threshold |
| Hydrocodone and acetaminophen | Lortab, Vicodin, Norco | Opioid and nonopioid analgesic combination | Pain | Side Effects: Dizziness, Drowsiness, N/V, Constipation, Respiratory depression |
| Oxycodone and acetaminophen | Percocet, Endocet, Roxicet | Opioid and nonopioid analgesic combination | Pain | Side Effects: Dizziness, Drowsiness, N/V, Constipation, Respiratory depression |
| Codeine and acetaminophen | Tylenol with Codeine #3 or #4 | Opioid and nonopioid analgesic combination | Pain | Side Effects: Dizziness, Drowsiness, N/V, Constipation, Respiratory depression |
| Naloxone | Narcan | Opioid antagonist | Opioid overdose | Side Effects: Headache, Opioid withdrawal syndrome, Pain, Diaphoresis Other notes: Potentially life-threatening respiratory depression; Addition of naloxone to buprenorphine reduces possibility of misuse by producing withdrawal symptoms when injected |
| Buprenorphine and naloxone | Suboxone | Partial opioid agonist and opioid antagonist | Opioid use disorder | Side Effects: Headache, Opioid withdrawal syndrome, Pain, Diaphoresis Other notes: Potentially life-threatening respiratory depression; Addition of naloxone to buprenorphine reduces possibility of misuse by producing withdrawal symptoms when injected |
| Methotrexate | Trexall | Antimetabolite | Rheumatoid arthritis, Crohn's disease, Psoriasis, Hematologic and solid tumors | Side Effects: Stomatitis, N/V, Leukopenia, Hepatic transaminases US BW: Serious toxic reactions; AVOID IN PREGNANCY; Do not take with NSAIDS; Methotrexate-induced lung disease Other notes: Folic acid may be taken to reduce hepatic and GI side effects |
| Anastrozole | Arimidex | Aromatase inhibitor | Hormone receptor-positive breast cancer | Side Effects: Fatigue, Rash, Flushing, Hot flashes, Arthralgia, N/V, Hypertension, Edema, Osteoporosis Other Notes: CV Side effects; Fetal toxicity AVOID IN PREGNANCY |
| Phentermine | Adipex-P | CNS Stimulant | Obesity | Side Effects: Hypertension, N/V, Dizziness, Xerostomia, Pulmonary Hypertension Other Notes: Only approved for short-term use; CI in those with history of CV disease or drug abuse, pregnancy, hyperthyroidism, or within 14 days of MAOI inhibitor therapy |
| Ferrous sulfate | FeroSul, SlowFe | Iron supplement | Iron deficiency anemia | Side Effects: Nausea, Upset stomach, Constipation, Dark and tarry stools US BW: Accidental overdose of iron is leading cause of fatal poisoning in children under 6 years old |
| Cyanocobalamin (Vitamin B12) | - | Water-soluble vitamin | Vitamin B12 deficiency | No major side effects |
| Folic acid | - | Water-soluble vitamin | Folic acid deficiency | No major side effects |