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Cardiovascular

Generic NameBrand namePharmacologic CategoryCommon IndicationsEssential Knowledge
Amiodarone Pacerone, Nexterone Antiarrhythmatic AF, Ventricular fibrilation, Ventricular tachycardia Key Side Effects: Hypothyroidism, Hyperthyroidism, pulmonary toxicity, hepatotoxicity US Boxed warnings: Life-threatening arrhythmias, pulmonary toxicity, hepatotoxicity Other notes: Many drug interactions
Digoxin Digitek, Digox, Lanoxin Cardiac glycoside AF, HF Key Side Effects: N/V, Visual changes Other notes: Narrow therapeutic range; signs of toxicity include N/V and visual changes; Many drug interactions
Ezetimibe Zetia Cholesterol absorption inhibitor Dyslipidemia Key Side Effects: Diarrhea
Fenofibrate Tricor, Trilipix Fibric acid derivative Dyslipidemia Key Side Effects: Dyspepsia, Myopathy/rhabdomyolysis, Elevated hepatic transaminases
Gemfibrozil Lopid Fibric acid derivative Dyslipidemia Key Side Effects: Dyspepsia, Myopathy/rhabdomyolysis, Elevated hepatic transaminases
Atorvastatin Lipitor HMG-CoA reductase inhibitor Dyslipidemia, CAD, Stroke Key Side Effects: Myopathy/rhabdomyolysis Other notes: Avoid excessive grapefruit juice intake, Avoid in pregnancy and breastfeeding
Lovastatin Mevacor HMG-CoA reductase inhibitor Dyslipidemia, CAD, Stroke Key Side Effects: Myopathy/rhabdomyolysis Other notes: Avoid excessive grapefruit juice intake, Avoid in pregnancy and breastfeeding
Pravastatin Pravachol HMG-CoA reductase inhibitor Dyslipidemia, CAD, Stroke Key Side Effects: Myopathy/rhabdomyolysis Other notes: Avoid excessive grapefruit juice intake, Avoid in pregnancy and breastfeeding
Rosuvastatin Crestor HMG-CoA reductase inhibitor Dyslipidemia, CAD, Stroke Key Side Effects: Myopathy/rhabdomyolysis Other notes: Avoid excessive grapefruit juice intake, Avoid in pregnancy and breastfeeding
Simvastatin Zocor HMG-CoA reductase inhibitor Dyslipidemia, CAD, Stroke Key Side Effects: Myopathy/rhabdomyolysis Other notes: Avoid excessive grapefruit juice intake, Avoid in pregnancy and breastfeeding
Omega-3 fatty acids Lovaza, Vascepa Omega-3 fatty acids Dyslipidemia Key Side Effects: Diarrhea, Nausea, Dysgeusia, Eructation
Niacin (ER) Niaspan Water-soluble vitamin Dyslipidemia Key Side Effects: Flushing, pruritus
Benazepril Lotensin Angiotensin-converting enzyme (ACE) inhibitor HTN, HF, CAD
Enalapril Vasotec Angiotensin-converting enzyme (ACE) inhibitor HTN, HF, CAD
Lisinopril Prinivil, Zestril Angiotensin-converting enzyme (ACE) inhibitor HTN, HF, CAD
Quinapril Accupril Angiotensin-converting enzyme (ACE) inhibitor HTN, HF, CAD
Ramipril Altace Angiotensin-converting enzyme (ACE) inhibitor HTN, HF, CAD
Irbesartan Avapro Angiotensin II receptor blocker (ARB) HTN, HF, CAD
Losartan Cozaar Angiotensin II receptor blocker (ARB) HTN, HF, CAD
Olmesartan Benicar Angiotensin II receptor blocker (ARB) HTN, HF, CAD
Valsartan Diovan Angiotensin II receptor blocker (ARB) HTN, HF, CAD
Valsartan and sacubitril Entresto ARB and neprilysin inhibitor (ARNI) HF
Amlodipine Norvasc Dihydropyridine calcium channel blocker (CCB) HTN, CAD
Nifedipine Procardia, Nifedical, Adalat Dihydropyridine calcium channel blocker (CCB) HTN, CAD
Nicardipine Cardene Dihydropyridine calcium channel blocker (CCB) HTN, CAD
Diltiazem Cartia, Cardizem Non-dihydropyridine CCB AF, HTN, CAD
Verapamil Calan, Verelan Non-dihydropyridine CCB AF, HTN, CAD
Hydrochlorothiazide Microzide Thiazide diuretic HTN
Chlorthalidone Thalitone Thiazide-related diuretic HTN
Metolazone Zaroxolyn Thiazide-related diuretic Volume overload
Amlodipine and benazepril Lotrel See individual drug components See individual drug components
Lisinopril and hydrochlorothiazide Prinzide See individual drug components See individual drug components
Losartan and hydrochlorothiazide Hyzaar See individual drug components See individual drug components
Olmesartan and hydrochlorothiazide Benicar-HCT See individual drug components See individual drug components
Triamterene and hydrochlorothiazide Dyazide, Maxzide See individual drug components See individual drug components
Valsartan and hydrochlorothiazide Diovan-HCT See individual drug components See individual drug components
Spironolactone Aldactone Potassium-sparing diuretic HTN, HF, ascites Key Side Effects: Gynecomastia, hyperkalemia
Bumetadine Bumex Loop diuretic Volume overload Key Side Effects: Hypokalemia, hypomagnesia, hyponatremia US Boxed Warning: Fluid and electrolyte loss
Furosemide Lasix Loop diuretic Volume overload Key Side Effects: Hypokalemia, hypomagnesia, hyponatremia US Boxed Warning: Fluid and electrolyte loss
Torsemide Demadex Loop diuretic Volume overload Key Side Effects: Hypokalemia, hypomagnesia, hyponatremia US Boxed Warning: Fluid and electrolyte loss
Atenolol Tenormin Beta1-selective beta-blocker AF, CAD, HTN Key Side Effects: Bradycardia Other notes: Masks symptoms of hypoglycemia US Boxed Warning: Avoid abrupt discontinuation
Metoprolol tartrate Lopressor Beta1-selective beta-blocker AF, CAD, HTN Key Side Effects: Bradycardia Other notes: Masks symptoms of hypoglycemia US Boxed Warning: Avoid abrupt discontinuation
Metoprolol succinate Toprolol-XL Beta1-selective beta-blocker HF, AF, CAD, HTN Key Side Effects: Bradycardia Other notes: Masks symptoms of hypoglycemia
Nebivolol Bystolic Beta1-selective beta-blocker HTN Key Side Effects: Bradycardia Other notes: Masks symptoms of hypoglycemia
Carvedilol Coreg Non-selective beta-blocker HF, AF, CAD, HTN Key Side Effects: Bradycardia Other notes: Masks symptoms of hypoglycemia
Labetalol Trandate Non-selective beta-blocker PO: HTN IV: Hypertensive crisis Key Side Effects: Bradycardia Other notes: Masks symptoms of hypoglycemia
Propranolol Inderal Non-selective beta-blocker HTN, CAD, Migraine prophylaxis Key Side Effects: Bradycardia Other notes: Masks symptoms of hypoglycemia US Boxed Warning: Avoid abrupt discontinuation
Clonidine Catapres Alpha2 agonist HTN, ADHD Key Side Effects: Xerostomia, drowsiness Other notes: Do NOT discontinue abruptly, taper to reduce rebound HTN US Boxed Warning: Avoid epidural use
Hydralazine Apresoline Direct arterial vasodilator HTN Key Side Effects: Orthostatic hypotension, Drug induced lupus like syndrome
Epinephrine Adrenalin Beta1, Beta2, and Alpha1 agonist Advanced cardiac life support, shock, anaphylaxis, bradycardia Key Side Effects: Tachyarrythmias, Peripheral ischemia, Lactic acidosis
Norepinephrine Levophed Alpha1 agonist (predominantly), Beta1 and Beta2 agonist Shock Key Side Effects: Tachyarrythmias, Peripheral ischemia US Boxed Warning: Extravasation (Central line administration preferred)
Dabigatran Pradaxa Anticoagulant, Direct thrombin inhibitor AF, VTE Key Side Effects: Bleeding, dyspepsia US Boxed Warning: Premature discontinuation increases risk of thrombotic events Other notes: Swallow whole; dispense and store in original packaging; discard 4 months after opening
Apixaban Eliquis Anticoagulant, Factor Xa inhibitor AF, VTE Key Side Effects: Bleeding US Boxed Warning: Premature discontinuation increases risk of thrombotic events
Rivaroxaban Xarelto Anticoagulant, Factor Xa inhibitor AF, VTE Key Side Effects: Bleeding US Boxed Warning: Premature discontinuation increases risk of thrombotic events
Warfarin Coumadin, Jantoven Anticoagulant, Vitamin K antagonist AF, VTE Key Side Effects: Bleeding US Boxed Warning: Bleeding risk Other notes: Narrow therapeutic index drug (toxicity may occur) Other notes: Dose dependent tablet colors; Uniform vit. K intake recommended; many drug interactions
Enoxaparin Lovenox Anticoagulant, Low molecular weight heparin ACS, VTE Key Side Effects: Bleeding, hyperkalemia, HIT US Boxed Warning: Increase risk of epidural hematoma in patient undergoing spinal puncture Other notes: Do NOT expel air bubble from syringe
Heparin - Anticoagulant ACS, VTE Key Side Effects: Bleeding, hyperkalemia, HIT
Clopidogrel Plavix Antiplatelet agent CAD, Stroke Key Side Effects: Bleeding US Boxed Warning: Diminished effectiveness in poor metabolizers
Dipyridamole and aspirin Aggrenox Antiplatelet agent Stroke Key Side Effects: Bleeding, headache
Prasugrel Effient Antiplatelet agent CAD Key Side Effects: Bleeding US Boxed Warning: Bleeding risk Other notes: CI in patients with history of stroke
Altepase Intracatheter: Cathflo IV: Activase Fibrinolytic Intracatheter: Catheter clearance IV: STEMI, Ischemic stroke, PE Key Side Effects: Bleeding Other notes: CI in patients with severe uncontrolled HTN
Created by: merandaharker
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