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ID 3 & 4

GenericBrandPharmacologic CategoryCommon IndicationsClassificationsEssential Knowledge
clindamycin (PO, IV) Cleocin Lincosamide antibiotic SSTI, pharyngitis Activity against: MRSA Key Side Effects: diarrhea, Clostridioides difficile diarrhea US Boxed Warning: Clostridioides difficile-associated diarrhea (CDAD) has been reported w/ use of nearly all antibacterial agents, including clindamycin, and may range in severity from mild di
sulfamethoxazole and trimethoprim (PO, IV) Bactrim, Bactrim DS Sulfonamide antibiotic SSTI, Cystitis, Pyelonephritis, Opportunistic infection prophylaxis Activity against: MRSA, Enterobacteriaceae Key Side Effects: nausea, vomiting, diarrhea, skin rashes (rarely SJS or TEN), photosensitivity, crystalluria, hyperkalemia, increased serum creatinine, hypersensitivity reactions
nitrofurantoin (PO) Macrobid Urinary antibiotic Cystitis Activity against: Escherichia coli Key Side Effects: nausea, pulmonary fibrosis (chronic use)
fosfomycin (PO) Monurol Urinary antibiotic Cystitis Activity against: Escherichia coli Key Side Effects: headache, nausea, diarrhea
vancomycin (IV, PO) Vancocin Glycopeptide antibiotic IV: SSTI, HAP, meningitis, endocarditis, CRBSI PO: CDI Activity against: MRSA, Clostridioides difficile (PO only) Key Side Effects: nephrotoxicity, vancomycin infusion reaction, ototoxicity
metronidazole Flagyl Antibiotic Anaerobic infections, CDI Activity against: Bacteroides species, Clostridioides difficile Key side Effects: nausea, metallic taste, disulfiram reaction w/ alcohol, peripheral neuropathy (long term use)
mupirocin (topical) Bactroban Antibiotic MRSA decolonization Key Side Effects: no major side effects
terbinafine (PO, topical) Lamisil Allylamine antifungal Onychomycosis Topical: OTC Key Side Effects: nausea, abdominal pain, diarrhea, elevated hepatic transaminases, headache
acyclovir (PO, IV) Zovirax Antiviral Herpes simplex virus Key Side Effects: nausea, increased hepatic transaminases, crystalluria
valacyclovir (PO) Valtrex Antiviral Herpes simplex virus Key Side Effects: nausea, increased hepatic transaminases
fluconazole (PO, IV) Diflucan Azole antifungal Vulvovaginal candidiasis, oropharyngeal candidiasis, invasive candidiasis Key Side Effects: nausea, abdominal pain, diarrhea, QTc prolongation, elevated hepatic transaminases
ketoconazole (PO, topical) Nizoral Azole antifungal Tinea infections Topical: OTC Key Side Effects: nausea, abdominal pain, diarrhea, QTc prolongation, increased hepatic transaminases US Boxed Warnings: serious hepatotoxicity, including cases with a fatal outcome or requiring liver transplantation have occurred; may cause QTc prolo.
oseltamivir (PO) Tamiflu Neuraminidase inhibitor antiviral Influenza Key Side Effects: nausea, vomiting, neuropsychiatric events in pediatric patients (rare)
nystatin (PO) —— Polyene antifungal Oropharyngeal candidiasis Key Side Effects: phlebitis, diarrhea, vomiting, anemia, fever
nystatin (topical) Nystop Polyene antifungal Cutaneous and mucocutaneous fungal infections Key Side Effects: burning, itching
micafungin (IV) Mycamine Echinocandin antifungal Invasive candidiasis Key Side Effects: no major side effects
betamethasone and clotrimazole (topical) Lotrisone Glucocorticoid and Azole antifungal Cutaneous fungal infections Key Side Effects: burning, itching, dryness, skin atrophy
tobramycin (IV, inhaled) Tobi (inhaled) Aminoglycoside antibiotic HAP, Cystic fibrosis (nebulized only) Activity against: Escherichia coli, Pseudomonas aeruginosa Key Side Effects: nephrotoxicity, ototoxicity
neomycin + polymyxin B + bacitracin (topical, ophthalmic) Topical: Neosporin Ophthalmic: Neo-Polycin Topical antibiotic Topical infection prevention Ocular infections Neosporin: OTC Key Side Effects: reddening, itching
nirmatrelvir + ritonavir (PO) Paxlovid Antiviral COVID-19 Key Side Effects: diarrhea, dysgeusia US Boxed Warnings: significant drug interactions; strong CYP3A inhibitor
remdesivir (IV) Veklury Antiviral COVID-19 Key Side Effects: hyperglycemia, renal impairment
emtricitabine + tenofovir disoproxil fumarate (PO) Truvada Nucleoside/Nucleotide Reverse Transcriptase Inhibitor (NRTI) HIV infection, PreP, PEP Key Side Effects: decreased bone mineral density, kidney injury, nausea, diarrhea US Boxed Warnings: post treatment acute exacerbation of hepatitis B, risk of drug resistance w/ use for preexposure prophylaxis
emtricitabine (NRTI) + tenofovir alafenamide (NRTI) + bictegravir (INSTI) (PO) Biktarvy Nuceloside/ Nucleotide Reverse Transcriptase Inhibitor (NRTI) and Integrase strand transfer inhibitor (INSTI) HIV infection Key Side Effects: increased serum bilirubin, headache, weight gain, insomnia, diarrhea, nausea US Boxed Warnings: post treatment acute exacerbation of hepatitis B
Created by: Kateloki
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