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Drug Interactions

QuestionAnswer
CYP 3A4 Inducers Decrease drug levels: Phenytoin, Phenobarbital, Oxcarbazepine, Carbamazepine, Rifampin, Smoking, SJW
CYP 3A4 Inhibitors Increase drug levels: Grapefruit, protease inhibitors, azole antifungals, cyclosporine, cobicistat, macrolides (clarithromycin, erythromycin), amiodarone, Non-DHP CCBs
Warfarin interactions that can increase INR CYP2C9 inhibitors: Amiodarone, azole antifungals, capecitabine, cimetidine, fluvastatin, fluvoxamine, metronidazole, tamoxifen, tigecycline, TMP/SMX, zafirlukast
Warfarin interactions that can decrease INR aprepitant, bosentan, carbamazepine, phenobarbital, phenytoin, primidone, rifampin, licorice, SJW
Created by: nakhla1
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