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The skeletal system has four components
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ANAPHY

Lec3 - Bones

QuestionAnswer
The skeletal system has four components bones, cartilage, tendons, and ligaments.
5 functions of skeletal system body support, organ protection, mineral storage, blood cell production, body movement
The principal minerals stored in the bones calcium and phosphorus
3 bone cells osteoblasts, osteocytes, osteoclasts
____________ are spaces in which bone cells are present. The main purpose of this in bone or cartilage is to provide a home for the cells it contains while also keeping them alive and functional. Lacunae
TRUE OR FALSE. In bones, lacunae encase osteocytes; in cartilage, lacunae enclose chondrocytes. TRUE
The _______________ is a double-layered outer layer of dense irregular connective tissue containing fibroblasts that most cartilage is covered by a protective connective tissue sheath. perichondrium
______________ cartilage, which is hyaline cartilage that covers the ends of bones where they come together to form joints, has no perichondrium, blood vessels, or nerves. Articular
In ______________ growth, chondroblasts in the perichondrium add new cartilage to the outside edge of the existing cartilage. appositional
In _____________ growth, chondrocytes in the center of the tissue divide and add more matrix in between the existing cells. interstitial
bone growth that enhances the length of the bone interstitial growth
bone growth that enhances the width of the bone appositional growth
This occurs when new cartilage is added to the surface of the cartilage by chondroblasts from the inner layer of the perichondrium. appositional growth
This occurs when new cartilage is formed within the cartilage by chondrocytes that divide and produce additional matrix. interstitial growth
By weight, mature bone matrix is normally about ____% organic and ____% inorganic material. 35%: 65%
The organic material in the bone matrix consists primarily of ____________ and _________________. collagen and proteoglycans
The inorganic material in the bone matrix consists primarily of a calcium phosphate crystal called ________________, which has the molecular formula Ca10(PO4)6(OH)2. hydroxyapatite
TRUE OR FALSE. If mineral in a long bone is reduced, collagen becomes the primary constituent, and the bone is overly brittle. FALSE. If mineral in a long bone is reduced, collagen becomes the primary constituent, and the bone is overly flexible.
TRUE OR FALSE. If the amount of collagen is reduced in the bone, the mineral component becomes the primary constituent, and the bone is very flexible. FALSE. If the amount of collagen is reduced in the bone, the mineral component becomes the primary constituent, and the bone is very brittle.
bone-building cells that have an extensive endoplasmic reticulum and numerous ribosomes; they also produce collagen and proteoglycans osteoblasts
The _______________ __________ act as templates that stimulate further hydroxyapatite formation and mineralization of the matrix. hydroxyapatite crystals
The formation of new bone by osteoblasts is called _______________, or _______________. ossification or osteogenesis
_________________ occurs by appositional growth on the surface of previously existing material, either bone or cartilage. Ossification
a thin layer of membranous connective tissue that covers all bones in the body periosteum
Once the osteoblasts have secreted sufficient bone matrix, they become what type of bone cells. Osteocytes
Bones have a lifespan of how many years? 25 years
Osteocytes account for ________% of bone cells and are very long-lived, with a lifespan of up to 25 years. 90-95
Osteocyte cell extensions are housed in narrow, long spaces called ____________. canaliculi
Breakdown of bone that are done by bone destroying cell (osteoclasts) is called _____________. bone reabsorption
_____________ is a fibrous protein that provides flexibility but resists pulling or compression. Collagen
Matrix ground substance contains _______________ which are water trapping proteins that help cartilage to be smooth and resilient. proteoglycans
It is a rare disorder caused by any one of a number of faulty genes that results in brittle bones, results in either too little collagen formation, or poor-quality collagen. Osteogenesis imperfecta
cells that maintain bone matrix and form from osteoblast after bone matrix has surrounded it osteocytes
These are functional units of compact bone. Osteons
The osteoclast plasma membrane then further differentiates into a highly folded form called the ___________ _________. ruffled border
a specialized reabsorption-specific area of the membrane ruffled border
As bone is broken down, the _____ goes into the blood. Ca2+
Osteoclasts Multistep Process • Access Bone Matrix • Sealed Compartment Under • Ruffled Border Reabsorption • Acidic Environment breakdown the matrix • Organic protein digestion • Products secreted into the bloodstream
TRUE OR FALSE. Osteoblasts are derived from osteochondral progenitor cells, and osteocytes are derived from osteoblasts. TRUE
Osteoclasts are derived from ______ ______ in red bone marrow. stem cells
two types of bone formed during ossification woven bone and lamellar bone
________ ______ is the first type of bone that osteoblasts form during ossification. It is fairly weak bone because the collagen fibers are randomly oriented in many directions. After this bone formation, osteoclasts break down the _______ _______ and osteoblasts build the stronger, more permanent lamellar bone. Woven bone
process of removing old bone and adding new bone bone remodeling
mature bone that is organized into thin, concentric sheets or layers approximately 3–7 micrometers (μm) thick called lamellae lamellar bone
TRUE OR FALSE. Compact bone has less bone matrix and more space than spongy bone, which has more bone matrix and less space. FALSE. Spongy bone has less bone matrix and more space than compact bone, which has more bone matrix and less space.
Spongy bone consists of interconnecting rods or plates of bone called _____________. trabeculae
thin columns and plates of bone that create a spongy structure in a cancellous bone, which is located at the ends of long bones and in the pelvis, ribs, skull, and vertebrae. trabeculae
What does trabeculae contain in spongy bone? lamellae, canaliculi, lacunae and osteocytes
other name of compact bone and spongy bone cortical bone (compact bone) trabecular bone/cancellous bone (spongy bone)
osteon is also called the ______________ ___________ haversian system
______________ are concentric rings of bone matrix which surround the central canal. Lamellae
Osteocytes are located in spaces called ___________ between the lamellar rings. lacunae
Small tunnels called ___________ radiate between lacunae across the lamellae. canaliculi
Surrounding the central canal are rings of bone matrix called ? concentric lamellae
If the osteocytes are found in lacunae in compact bone, where does osteocytes reside in spongy bone? Instead, the lacunae and osteocytes are found in a lattice-like network of matrix spikes called trabeculae (singular = trabecula)
This bone has more matrix, denser, less space, blood vessels enter the substance of the bone itself, and the lamellae of compact bone of compact bone are primarily oriented around those blood vessels. Compact bone
____________________ lamellae form the outer surfaces of compact bone, which are thin plates that extend around the bone. Circumferential lamellae
Between the osteons are ______________ lamellae, which are remnants of concentric or circumferential lamellae that were partially removed during bone remodeling. interstitial
______________ _________ (Volkmann canals) deliver blood to the central canals of the osteons. The canals run perpendicular to the length of the bone. They contain blood vessels from the periosteum or medullary cavity. Perforating canals
The _____________ is the center portion of the bone which is composed of compact bone surrounding a hollow center called the ____________ _________. diaphysis: medullary cavity
The ends of a long bone are called ____________.They contain mostly spongy bone, with an outer layer of compact bone. epiphyses
Spongy bone is found mostly at the ends of bones and contains __________ ____________. red marrow
This type of bone marrow can be found in the medullary cavity in the shaft of long bones and is often surrounded by a layer of red bone marrow. yellow bone marrow
TRUE OR FALSE. Long bones are longer than they are wide. TRUE
TRUE OR FALSE. Short bones are wider than they are long. FALSE. They are round or nearly cubed-shaped.
Give examples of long bones. Long bones are found in the arms (humerus, ulna, radius) and legs (femur, tibia, fibula), as well as in the fingers (metacarpals, phalanges) and toes (metatarsals, phalanges).
Give examples of short bones. The carpals in the wrist (scaphoid, lunate, triquetrium, hamate, pisiform, capitate, trapezoid, and trapezium) and the tarsals in the ankles (calcaneus, talus, navicular, cuboid, lateral cuneiform, intermediate cuneiform, and medial cuneiform) are examples of short bones.
These are bone shapes that are thin, flattened shape and are usually curved. Flat bones
Give examples of flat bones. cranium (skull), the ilium, ischium, and pubis (pelvis), sternum and the rib cage; the flat bones are: the occipital, parietal, frontal, nasal, lacrimal, vomer, sternum, ribs, and scapulae.
Bone shape that vary in shape and structure and therefore do not fit into any other category (flat, short, long, or sesamoid). They often have a fairly complex shape, which helps protect internal organs. Irregular bones
Give examples of irregular bones. the vertebræ, sacrum, coccyx, temporal, sphenoid, ethmoid, zygomatic, maxilla, mandible, palatine, inferior nasal concha, and hyoid.
The _________________ ________ is located between the epiphysis and the diaphysis. Growth in bone length occurs at the _______________ ________. epiphyseal plate
When bone stops growing in length, the epiphyseal plate becomes ossified and is called the ________________ ______. epiphyseal line
Cavities in spongy bone and the medullary cavity in the diaphysis are filled with soft tissue called __________. marrow
_____ marrow is the location of blood forming cells. Red
_________ marrow is mostly fat/ adipose tissue. Yellow
TRUE OR FALSE. In adults, most red bone marrow is in the irregular bones. FALSE. In adults, most red bone marrow is in the flat bones.
What color of bone marrow is present in the medullary cavity of juveniles? red marrow (yellow marrow for adults)
The outer surface of a bone is covered by a connective tissue membrane called _______________. periosteum
What does the outer layer of periosteum contain? blood vessels and nerves
What does the inner layer of periosteum contain? a single layer of bone cells, including osteoblasts, osteoclasts, and osteochondral progenitor cells.
a single cell layer of connective tissue that lines the internal surfaces of all cavities within bones endosteum
What bone cells does endosteum contain? The endosteum includes osteoblasts and osteoclasts.
Within joints, the end of a long bone is covered with hyaline cartilage called _________________ ______________. articular cartilage
Shaft of the bone diaphysis
End of the bone; develops from its own center of ossification epiphysis
Outer, double-layered connective tissue membrane with ligaments and tendons attached to bone through the this; blood vessels and nerve pathways; this is where bone grows in diameter periosteum
Thin connective tissue membrane lining the inner cavities of bone endosteum
Thin layer of hyaline cartilage covering a bone where it forms a joint (articulation) with another bone articular cartilage
Hyaline cartilage between the diaphysis and epiphysis; its growth allows for growth in bone length epiphyseal plate
Bone having many small spaces; found mainly in the epiphysis; arranged into trabeculae spongy bone
Dense bone with few internal spaces organized into osteons; forms the diaphysis and covers the spongy bone of the epiphyses compact bone
Large cavity within the diaphysis medullary cavity
Connective tissue in the spaces of spongy bone or in the medullary cavity; the site of blood cell production red marrow
Fat stored within the medullary cavity or in the spaces of spongy bone yellow marrow
The primary ossification center is in what part of a long bone? diaphysis
(LONG BONE PART) Growth in bone length occurs at the between the epiphysis and diaphysis. epiphyseal plate or growth plate
TRUE OR FALSE. In adults, the spaces within bones are filled with red marrow FALSE. In the fetus, the spaces within bones are filled with red marrow.
TRUE OR FALSE. Yellow marrow completely replaces the red marrow in the long bones of the limbs, except for some red marrow in the proximal part of the arm bones and thigh bones. TRUE
(BONE SHAPE) Outer layers of compact bone surround spongy bone flat bones
Do irregular and short bones are elongated and have diaphyses? Short and irregular bones are not elongated and have no diaphyses.
2 processes of bone formation intramembranous ossification and endochondral ossification
Intramembranous ossification starts within _____________ connective tissue membranes. embryonic
Endochondral ossification starts with a _____________ model. cartilage
(BONE FORMATION) Begins 8th week of embryonic development and is completed by approximately 2 yrs of age Intramembranous Ossification
(BONE FORMATION) This occurs primarily in the bones of the skull (cranium), lower jaw, clavicles Intramembranous Ossification
(BONE FORMATION) Osteoblasts line up on the surface of connective tissue fibers and begin depositing bone matrix to form trabeculae. Intramembranous Ossification
(BONE FORMATION) The process begins in areas called ossification centers and the trabeculae radiate out from the centers. Intramembranous Ossification
(BONE FORMATION) Usually, two or more ossification centers exist in each flat skull bone and mature skull bones result from fusion of these centers as they enlarge. Intramembranous Ossification
(BONE FORMATION) The trabeculae are constantly remodeled and they may enlarge or be replaced by compact bone. Intramembranous Ossification
The locations in the membrane where ossification begins are called _______________ ___________. ossification centers
The steps in intramembranous ossification osteoblast formation > spongy bone formation > compact bone formation
end products of intramembranous bone formation outer compact bone surfaces and spongy centers
soft spots, are the larger, membrane covered spaces between the developing skull bones that have not yet been ossified fontanels
the future site of the BREGMA- it will close by 18 months old. (7-19 months) anterior fontanelle
the future site of the LAMBDA – it will begin to close during the first few months after birth. (1-3months) posterior fontanelle
Fontanelle closes around 6 months after birth sphenoidal fontanelle
Fontanelle closes from 6-18 months after birth mastoid fontanelle
coronal + sagittal suture BREGMA
lambdoid + sagittal suture LAMBDA
frontal + temporal + parietal + greater wing of sphenoid PTERION
parietomastoid + occipitomastoid + lambdoid ASTERION
meeting point of frontal and nasal bones NASION
(BONE FORMATION) Cartilage formation Begins at the end of 4th week of embryonic development Endochondral Ossification
(BONE FORMATION) Endochondral bone formation starts at 8th week of embryonic development but might not begin in other cartilage until as late as 18-20 yrs of age Endochondral Ossification
(BONE FORMATION) This occurs primarily in the base of the skull, part of the mandible, epiphysis of clavicle, and the remaining skeletal system Endochondral Ossification
(BONE FORMATION) Initially formed is a primary ossification center, which forms bone in the diaphysis of a long bone. Endochondral Ossification
What replaces the cartilage model in endochondral ossification? bone
(BONE FORMATION) A secondary ossification center forms bone in the epiphysis. Endochondral Ossification
The steps in endochondral ossification Cartilage model formation Bone collar formation Primary ossification center formation Secondary ossification center formation Adult bone
This type of bone growth occurs through endochondral ossification. Bone growth in length
Growth in the length of a bone, which is the major source of increased height in an individual, occurs in the ___________________ ___________. epiphyseal plate
(BONE GROWTH IN LENGTH) _________________ increase in number on the epiphyseal side of the epiphyseal plate. Chondrocytes
(BONE GROWTH IN LENGTH) The osteoblasts start forming bone by depositing bone ______________ on the surface of the calcified cartilage. lamellae
bone cell - removal of existing bone osteoclasts
bone cell - deposition of new bone osteoblasts
Does bone remodeling occur in all bones? Yes.
steps of bone repair hematoma formation callus formation callus ossification bone remodeling
Calcium is a critical nutrient involved in many physiological processes including: • Stimulation and regulation of skeletal and cardiac muscle contraction • Exocytosis of cellular molecules, including those important for neural signaling
major site of calcium bones
Calcium moves _____ bone as osteoblasts build new bone. into
Calcium moves ____ of bone as osteoclasts break down bone. out
Calcium homeostasis is maintained by _____________ hormone (PTH) and calcitonin. parathyroid
Secreted by the parathyroid gland Parathyroid Hormone (PTH)
Increases formation and activation of osteoclasts, the principal bone-reabsorbing cells Parathyroid Hormone (PTH)
Stimulates reabsorption of Ca2+ from urine in the kidney, reducing the amount of Ca2+ excreted in the urine. Parathyroid Hormone (PTH)
Indirectly increases Ca2+ uptake from the small intestine through the activation of calcitriol. Parathyroid Hormone (PTH)
Secreted from C cells in the thyroid gland when blood Ca2+ levels are too high Calcitonin
Rapidly lowers blood Ca2+ levels by inhibiting osteoclast activity Calcitonin
Bones are segregated into the ...... axial skeleton and the appendicular skeleton.
The average adult has _____ bones. 206
The axial skeleton consists of the bones of the ...... skull, the auditory ossicles, the hyoid bone, the vertebral column, and the thoracic cage.
The term ________, refers to the two zones where the limbs are attached to the body. girdle
The appendicular skeleton consists of the bones of the ....... upper limbs, the lower limbs, and the two girdles.
2 girdles in the axial skeleton pectoral girdle & pelvic girdle
(Anatomical Terms for Bone Features) Main part body
(Anatomical Terms for Bone Features) Enlarged, often rounded end head
(Anatomical Terms for Bone Features) Constriction between head and body neck
(Anatomical Terms for Bone Features) Edge margin/border
(Anatomical Terms for Bone Features) Bend angle
(Anatomical Terms for Bone Features) Branch off the body beyond the angle ramus
(Anatomical Terms for Bone Features) Smooth, rounded articular surface condyle
(Anatomical Terms for Bone Features) Small, flattened articular surface facet
(Anatomical Terms for Bone Features) Low ridge line, linea
(Anatomical Terms for Bone Features) Prominent ridge crest, crista
(Anatomical Terms for Bone Features) Very high ridge spine
(Anatomical Terms for Bone Features) Prominent projection process
(Anatomical Terms for Bone Features) Small, rounded projection tubercle
(Anatomical Terms for Bone Features) Rounded projection; larger than a tubercle tuberosity; tuber
(Anatomical Terms for Bone Features) Tuberosity on the proximal femur trochanter
(Anatomical Terms for Bone Features) Upon a condyle epicondyle
(Anatomical Terms for Bone Features) Flat, tongue-shaped process lingula
(Anatomical Terms for Bone Features) Hook-shaped process hamulus
(Anatomical Terms for Bone Features) Horn-shaped process horn/ cornu
(Anatomical Terms for Bone Features) Hole foramen
(Anatomical Terms for Bone Features) Tunnel canal, meatus
(Anatomical Terms for Bone Features) Cleft fissure
(Anatomical Terms for Bone Features) Cavity sinus, labrynth
(Anatomical Terms for Bone Features) General term for a depression fossa
(Anatomical Terms for Bone Features) Depression in the margin of a bone notch
(Anatomical Terms for Bone Features) Little pit fovea
(Anatomical Terms for Bone Features) Deep, narrow depression groove, sulcus
immovable joints sutures
four principal sutures • coronal (frontal + parietal) • sagittal (2 parietal bones) • lambdoid (occipital + parietal) • squamous (parietal + temporal)
Anterior part of cranium, the ‘forehead” Frontal bone
Sides and roof of cranium Parietal bone
Posterior portion and floor of cranium Occipital bone
Inferior to parietal bones on each side of the cranium; where temporomandibular joint is attached Temporal bones
Forms part of cranium floor, lateral posterior portions of eye orbits, lateral portions of cranium anterior to temporal bones; where sella turcica is found Sphenoid bone
Anterior portion of cranium, including medial surface of eye orbit and roof of nasal cavity; nasal conchae Ethmoid bone
Give the cranial bones. frontal, temporal, parietal, occipital, sphenoid, and ethmoid
Forms the upper jaw, anterior portion of hard palate, part of lateral walls of nasal cavity, floors of eye orbits; maxillary sinus Maxillae
Form posterior portion of hard palate, lateral wall of nasal cavity Palatine bones
Cheek bones; also form floor and lateral wall of each eye orbit Zygomatic bones
Medial surfaces of eye orbits Lacrimal bones
Form bridge of nose Nasal bones
In midline of nasal cavity; forms nasal septum with the ethmoid bone Vomer
Attached to lateral walls of nasal cavity Inferior nasal conchae
Lower jawbone; only movable skull bone Mandible
The paranasal sinuses are: • Maxillary • Ethmoid • Sphenoid • Frontal
Paranasal sinuses that are present at birth and are not? (PRESENT AT BIRTH) Maxillary & Ethmoid (NOT PRESENT AT BIRTH)) Sphenoid & Frontal
First radiological evidence of the paranasal sinuses? Maxillary (4-5 months at birth) Ethmoid (1 year) Sphenoid (4 years) Frontal (6 years)
When does the maxillary, sphenoid, ethmoid and frontal sinuses reach adult size? Maxillary (15 years) Ethmoid (12 years) Sphenoid (15 years-adult age) Frontal (size increases until teens)
A bone that is unpaired, U-shaped bone that is not part of the skull and has no direct bony attachment to the skull or any other bones. Hyoid bone
The only bone that has a unique distinction since it is the only bone in the body that does not articulate with another. bone. Hyoid bone
This bone provides an attachment for some tongue muscles, and it is an attachment point for important neck muscles that elevate the larynx. Hyoid bone
It is the central axis of the skeleton, extending from the base of the skull to slightly past the end of the pelvis. Vertebral column or spine
How many vertebrae are present in babies and in adults? babies (33); adults (26)
The adult vertebral column has four major curvatures: cervical, thoracic, lumbar and sacrococcygeal
A vertebral region that curves posteriorly. thoracic, sacral, and coccygeal
A vertebral region that curves anteriorly. cervical & lumbar
1st vertebra; holds head Atlas
2nd vertebra; rotates head Axis
Functions of Vertebral Column • Supports body weight • Protects the spinal cord • Allows spinal nerves to exit the spinal cord • Provides a site for muscle attachment • Provides movement of the head and trunk
Bones that protects vital organs; 12 pair of ribs Thoracic cage
Also called the breastbone sternum (manubrium, body, and xiphoid process)
Ribs that are attach directly to sternum by cartilage. True ribs (1-7)
Ribs that attach indirectly to sternum by cartilage. False ribs (8-12)
Ribs that are not attached to sternum but to the thoracic vertebrae. Floating ribs (11-12)
Also called shoulder blade Scapula
Also called collar bone Clavicle
Proximal row carpal bones Scaphoid, Lunate, Triquetrium, Pisiform
Distal row carpal bones Hamate, Capitate, Trapezoid, Trapezium
Where lower limbs attach to the body Pelvic girdle
includes pelvic girdle and coccyx Pelvis
inferior and posterior region of hip bone Ischium
most superior region of hip bone Ilium
hip socket (joint) of hip bone Acetabulum
Also called thigh Femur
Also called knee cap Patella
Larger bone of lower leg Tibia
Smaller bone lower leg Fibula
Ankle Tarsals
Foot Metatarsals
Toes and fingers Phalanges
where two bones come together Articulations (joints)
(Structural Classification of Joints) united by fibrous connective tissue; subclasses are sutures, syndesmosis, and gomphoses Fibrous joints
(Structural Classification of Joints) united by means of cartilage; subclasses are synchondroses and symphysis Cartilaginous joints
(Structural Classification of Joints) joined by a fluid cavity; most joints of the appendicular skeleton Synovial joint
(Functional Classification of Joints) non-movable joint; example – skull bone articulations Synarthrosis
(Functional Classification of Joints) slightly movable joint; example - between vertebrae Amphiarthrosis
(Functional Classification of Joints) freely movable joint; example - knee, elbow, and wrist articulations Diarthrosis
cartilaginous joint where the bones are joined by hyaline cartilage synchondrosis
cartilaginous joint where the bones are joined by fibrocartilage. symphysis
fibrous joints that unites parallel bones syndesmosis
Subclasses of Synovial joints (PLAY GUITAR TO ENJOY SAD SATURDAY BONDINGS) Plane, Ginglymus, Trochoid, Ellipsoid, Sellar, Spheroidal, Bicondylar
Subclasses of Cartilaginous joints Symphysis & Synchondrosis
Subclasses of Fibrous joints Syndesmosis, Sutures, Gomphoses
The ___________________ ____________ (Capsula articularis atlantooccipitalis) is an articulation between the atlas bone and the occipital bone. It consists of a pair of condyloid joints. It is a synovial joint. atlanto-occipital joint
The cavity is created by the ________ __________ and is full of synovial fluid filled _________ ___________. joint cavity; joint capsule
The ________ ___________ helps hold the bones together while still allowing for movement. joint capsule
The joint capsule consists of two layers: an outer fibrous capsule and an inner synovial membrane.
The ________ ____________ is the outer layer of the joint capsule. It consists of dense irregular connective tissue and is continuous with the fibrous layer of the periosteum that covers the bones united at the joint. fibrous capsule
The _____________ _______________ is the inner layer of the joint capsule. It lines the joint cavity, produces synovial fluid, a viscous lubricating liquid. synovial membrane
(Types of Movement) straightening of a joint Extension
(Types of Movement) movement away from midline Abduction
(Types of Movement) bending of a joint Flexion
(Types of Movement) movement toward the midline Adduction
(Types of Movement) rotation of the forearm with palms down Pronation
(Types of Movement) rotation of the forearm with palms up Supination
(Types of Movement) movement of a structure about the long axis Rotation
Effects of Aging on the Skeletal System and Joints 1. Decreased Collagen Production 2. Loss of Bone Density 3. Degenerative Changes
Functional Classification of Joints Synarthrosis, Amphiarthrosis, DIarthrosis
Bone, cartilage, tendons, and ligaments of the skeletal system are all what type of tissues? Connective tissues
The characteristics of bones, cartilage, tendons and ligaments are largely determined by the composition of their ______. ECM (extracellular matrix)
The extracellular matrix of tendons and ligaments contains large amounts of ____________ _________, making these structures very tough, like ropes or cables. collagen fibers
What component gives the bone compression (weight-bearing) strength? mineral
Osteoblasts are responsible for the formation of bone and the _________ and _______________ of bone. repair; remodeling
Osteoblasts produce what organic materials? collagen and proteoglycans
Created by: yulyae
 

 



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