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DSM drugs list 3
Third category must know drugs list, class, indications, mec
| Question | Answer |
|---|---|
| 1 Amiloride | K sparing, dist tub. |
| 2 Bromocriptine | relieves Sx parkinsonism, decr levels of GH in acromegaly |
| 3 Carbimazole | converted to methimazole which decr. Thyroid hormone production. |
| 4 Calciferol | activated vit D |
| 5 Chloroquine | antimalarial. Prophylactic and treatment. |
| 6 Clopidogrel | antiplatelet |
| 7 Cyclophosphamide | lymphoma, multiple myeloma, leukemia, neuroblastoma, ovarian and breast cancer. Mechanism involves crosslinking tumour DNA. |
| 8 Cyclosporin | potent immune suppressant, after transplants. Also Rx psoriasis, RA |
| 9 Dobutamine | beta 1 agonist, ionotropic, short term treatment cardiac decompensation, eg in heart surgery |
| 10 Etanercept | TNF inhibitor. Rx autoimmune eg Ank spon, RA, psoriasis, psoriatic arthritis. |
| 11 Fentanyl | opioid analgesic, esp post op. |
| 12 Filgrastim | G-CSF, incr neutrophils. Used with chemo (esp leukemias), and in patients getting marrow transplants. |
| 13 Fludrocortisone | replace aldosterone in addisons. |
| 14 Fluconazole | fungal. Triazole |
| 15 Gabapentin | antiepileptic and post-herpetic neuralgia |
| 16 Halothane | inhalation GA, induction and maintenance. |
| 17 Lignocaine | LA block Na |
| 18 Loratidine | antihistamine for runny eyes etc, allergies |
| 19 Mesalazine | aminosalicilic. Antinflam. Crohns, UC. |
| 20 Methylphenidate | CNS stimulant. ADD, narcolepsy. |
| 21 Nitrous oxide | anaesthetic, maintenance, also childbirth, ED, pre-hospital care. Entonox 50% O2. |
| 22 Ritanovir | protease inhibitor HIV, possibly also spelt ritonavir |
| 23 Suxamethonium | aka succinylcholine. Paralytic, used before intubation. Simulates acetylcholine on muscle type nicotinic receptors, but broken down much slower. |
| 24 tamoxifen | competitive antagonist to oestrogen, used in ER+ breast cancer |
| 25 thiopentone | rapid onset short acting barbiturate anaesthetic. Increases inhibitory activity of GABAa receptor (as all barbit., benzodiaz. and alcohol) |
| 26 tramodol | agonist mu opioid rec. 5-HT release, NA reuptake inhib. Pain killer, also restless leg syndrome. |
| 27 tubocurarine | long-duration antagonist ACh neuromusc. Nicotinic rec. Paralysis voluntary musc. Including diaphragm. Rocuronium is safer |
| 28 vancomycin | glycopeptides Abx, gram +, Abx of last resort with resistant strains. |
| 29 zidovudine | INN/azidothymidine (AZT). Analogue of thymidine. Class of nucleoside analogue reverse transcriptase inhibitor (NRTI), used in conjunction with other antivirals in HIV/AIDS |