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DSM drugs list 1

First category must know drugs list, class, indications, mechanism

QuestionAnswer
1 Allopurinol Gout. Xanthine Oxidase inhib.
2 Amitriptyline TCA. NA, 5-HT reuptake inhib.
3 Aspirin analgesic, antiplatelet. Irrevers COX1/2 inhib..
4 Atropine Antichol, organophos. Poisoning. Rx bradycardia, asystole, PEA.
5 Bendrofluazide HPN, mild HF. Thiazide diuretic. Distal tub inhib NaCl reabs.
6 Codeine analgesic. Antitussive. Anti-diarrhoea. Binds opioid rec. Metabolised in liver to morphine.
7 Colchicine Gout. Also anti-mitotic.
8 Diazepam short term anxiety (up to 6 wks). Sedation. IV status epilepticus. Binds GABA rec. incr chance opens. Allosterically incr. GABA mediated inhib.
9 Diclofenac (voltarenTM) NSAID. COX inhib. Mech see aspirin. Antipyretic. Decr PGE2 synthesis in hypothalamus to decr. Temp.
10 Digoxin Congestive HF. Control ventricular rate in AF. Cardiogenic shock. +ionotropic (F), -chronotropic (decr HR). Slow SA node conduction. Prolong refractory period bundle His. Extra Ca2+ available contraction.
11 Diltiazem Antiarrhyth (class IV). HPN. Angina (incl vasospasm). Ca2+ chan blocker. Decr Ca2+, slow AV conduction -> decr HR. Relax smooth musc -> decr periph resistance.
12 Enalapril HPN. Renal HPN. HF. ACE inhib.
13 Enoxaparin LMWH. Higher anti Xa to antithrombin activity ratio than heparin. Surgery. Rx DVT/PE
14 Erythromycin macrolide Abx. Broad spectrum. Gram +. Inhib bact prot synth.
15 Ethanol alcohol.
16 Fluticasone steroid, Cream skin, spray asthma preventer
17 Frusemide loop diuretic, inhib Na/K 2Cl transporter
18 Gentamicin aminoglycoside oto and renal toxicity
19 Gliclazide sulphonylurea. Stim insul release pancr.
20 GTN NO released from endoth. -> SM, vasodilates angina
21 Haloperidol antipsychotic/neuroleptic. Butyrophenones class..
22 Insulin sugar lowering peptide
23 Methadone opioid, long acting
24 Metoprolol sel beta1 block, decr HR and contractility. HPN, arryth
25 Metronidazole Abx, anaerobes, protozoa, gut and gyne surgery, leg wound/ulcer infections. H pylori, c dif (when gut flora suppressed.. causes pseudomembranous colitis)
26 Morphine opioid analgesic
27 Nicotine addictive thing cigarettes, raises BP.
28 Omeprazole PPI, GORD
29 OC progestagens, combined +estrogens
30 Paracetamol acetaminophen. antipyretic analgesic, class aniline analgesic
31 Paroxetine SSRI
32 Penicillin Abx, aminopenicillins include amoxi, fluclox, ampicillin
33 Phenytoin Dilantin TM anti epileptic, old. Na block, decr glutamate release
34 Prednisone steroid, anti inflame, anti allergic
35 Risperidone antipsychotic, block DA, 5-HT
36 Salbutamol adrenergic bronchodilator, ventolin. COPD, asthma
37 Simvastatin lipid lowering, HMG CoA reductase inhib
38 Spironolactone aldost blocked dist. Tub. K+ sparing diuretic. HPN. Oedema in chronic HF
39 Temazepam benzodiazepine, anxiolytic. Short term use (4 wks) insomnia.
40 Valproate epilim TM , anti-convulscent, incr GABA conc
41 Warfarin anticoag, vit K antag, takes 3-4 days take effect
Created by: briary
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