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Thyroid Drugs
Question | Answer |
---|---|
What is the most common drug prescribed for hypothyroidism? | Levothyroxine (Synthroid & Levoxyl) |
How long does it take for symptoms of hypothyroidism to improve after synthroid is started? Why? | 28-35 days, because synthroid is composed of T4 which has a long half-life (7 days) |
What will levothyroxine do to thyroid hormones in the body? | T3 & T4 will be increased and TSH will be decreased |
What drug is used to treat the most severe form of hypothyroidism, myxedema coma? | Liothyronine (Cytomel) |
Side Effects with thyroid drugs are rare, but when they occur what are they? | increased cardiac output, CNS excitation, and thyrotoxicosis (increased temp, severe tachycardia, dysrhythmias, muscle weakness, coma, and death) |
If Liothyronine therapy is effective what will happen to thyroid hormone levels? | T4 will not increase, but TSH will decrease |
Antithyroid Drugs treat what condition? | Hyperthyroidism |
List symptoms of Grave's Disease. | fast metabolic rate, weight loss, increased heart rate, dysrhythmias, restlessness, nervousness, insomnia, increased temp, flushed hot sin, increased levels of T3 & T4 |
List Antithyroid Drugs. | Tapazole (methimazole), PTU (propothiouracil) |
What is a side effect associated with Tapazole? | agranulocytosis |
What is a side effect associated with PTU? | rash |
List two Iodides. | SSKI (saturated solution of potassium iodide), Lugol's solution |
What do Iodides do? | suppress T3 & T4 synthesis |
When are Iodides used? | Prior to thyroid gland removal |
How often are iodides taken before sugery? | Tid for 10 days before surgery |
What are side effects of Iodides? | Iodism: metallic taste, excess salivation, swelling of salivary glands, nausea, skin changes |