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CV 3

GenericBrandPharm CategoryIndicationEssential Knowledge
Dabigatran (PO) Pradaxa Anticoagulant, direct thrombin inhibitor AF (stroke prevention), VTE Key Side Effects: bleeding, dyspepsia US Boxed Warnings: premature discontinuation increases risk of thrombotic events Other Notes: swallow whole; dispense/ store in original packaging; discard 4 months after opening
Apixaban (PO) Eliquis Anticoagulant, factor Xa inhibitor AF (stroke prevention), VTE Key Side Effects: bleeding rivaroxaban (PO) Xarelto US Boxed Warnings: premature discontinuation increases risk of thrombotic events
Rivaroxaban (PO) Xarelto Anticoagulant, factor Xa inhibitor AF (stroke prevention), VTE Key Side Effects: bleeding rivaroxaban (PO) Xarelto US Boxed Warnings: premature discontinuation increases risk of thrombotic events
Warfarin (PO) Coumadin, Jantoven Anticoagulant, vitamin K antagonist AF (stroke prevention), VTE Key Side Effects: bleeding US Box Warning: bleeding risk Notes: narrow therapeutic (toxicity may occur at conc close to therapeutic range; monitoring recommended with INR), dose dependent tablet colors; uniform vitamin K intake recommended; many DDI
Enoxaparin (SQ) Lovenox Anticoagulant, low molecular weight heparin ACS (Acute Coronary Syndrome), VTE Key Side Effects: bleeding, hyperkalemia, HIT US Boxed Warnings: increased risk of epidural or spinal hematoma in patient undergoing spinal puncture Notes: do not expel air bubble from syringe prior to injection
Heparin (IV, SQ) --- Anticoagulant ACS (Acute Coronary Syndrome), VTE Key Side Effects: bleeding, hyperkalemia, HIT
Clopidogrel (PO) Plavix Antiplatelet agent CAD, stroke Key Side Effects: bleeding US Boxed Warnings: diminished effectiveness in poor metabolizers
Dipyridamole & aspirin (PO) Aggrenox Antiplatelet agent Stroke Key Side Effects: bleeding, headache
Prasugrel (PO) Effient Antiplatelet agent CAD Key Side Effects: bleeding US Boxed Warnings: bleeding risk Notes: CI in patients with history of stroke
Alteplase (intracatheter, IV) Intracatheter: Cathflo IV: Activase Fibrinolytic Intracatheter: catheter clearance IV: STEMI, ischemic stroke, PE (pulmonary embolism) Key Side Effects: bleeding Notes: CI in patients with severe uncontrolled HTN
Created by: Aware19
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