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ADEs/PRECAUTIONS
ADES + PRECAUTIONS
| Drug | ADE/Precaution |
|---|---|
| Aminoglycosides | Nephrotoxicity, Ototoxicity, Neuromuscular blockade |
| Aminoglycosides | Monitor renal function, avoid in pregnancy |
| Amphotericin B | Nephrotoxicity, Infusion reactions, Hypokalemia, Hypomagnesemia |
| Amphotericin B | Pre-medicate for infusion reactions, monitor electrolytes |
| Warfarin | Bleeding, Teratogenicity |
| Warfarin | Regular INR monitoring, avoid in pregnancy |
| Statins | Myopathy, Hepatotoxicity |
| Statins | Monitor liver enzymes and CK, especially if muscle symptoms |
| Lithium | Nephrotoxicity, Thyroid dysfunction, Tremor |
| Lithium | Regular monitoring of renal function and thyroid tests |
| Methotrexate | Hepatotoxicity, Myelosuppression, Mucositis |
| Methotrexate | Monitor liver function tests and CBC, folate supplementation |
| ACE Inhibitors | Cough, Hyperkalemia, Angioedema |
| ACE Inhibitors | Monitor potassium, avoid in pregnancy |
| Beta Blockers | Bradycardia, Hypotension, Bronchospasm in asthma |
| Beta Blockers | Monitor heart rate and BP, caution in asthma |
| Digoxin | Arrhythmias, Visual disturbances |
| Digoxin | Monitor serum levels, especially with renal impairment |
| Phenytoin | Gingival hyperplasia, Hirsutism, Neuropathy, Teratogenicity |
| Phenytoin | Monitor serum levels, avoid in pregnancy |
| Corticosteroids | Hyperglycemia, Osteoporosis, Immunossuppression |
| Corticosteroids | Bone protection in long-term use, monitor blood sugar |
| SSRIs | Sexual dysfunction, Serotonin syndrome, Weight changes |
| SSRIs | Monitor for mood changes, serotonin syndrome symptoms |
| Clopidogrel | Bleeding, Thrombotic thrombocytopenic purpura |
| Clopidogrel | Monitor for signs of bleeding, platelet counts |
| NSAIDs | GI bleeding, Renal impairment, Cardiovascular risk |
| NSAIDs | Use with caution in patients with GI or kidney diseases |
| Bisphosphonates | Osteonecrosis of the jaw, Esophagitis |
| Bisphosphonates | Adequate dental hygiene, remain upright after dosing |
| Tetracyclines | Photosensitivity, Teeth discoloration, GI upset |
| Tetracyclines | Avoid in children and pregnancy, sun protection |
| Sulfa Drugs | Stevens-Johnson Syndrome, Hematologic abnormalities |
| Sulfa Drugs | Monitor for skin reactions and blood disorders |
| Antipsychotics | Extrapyramidal symptoms, Tardive dyskinesia, Neuroleptic malignant syndrome |
| Antipsychotics | Monitor for movement disorders, neurologic symptoms |
| Calcium Channel Blockers | Peripheral edema, Constipation, Bradycardia |
| Calcium Channel Blockers | Monitor blood pressure and heart rate |
| MAO Inhibitors | Hypertensive crisis with certain foods, Serotonin syndrome |
| MAO Inhibitors | Dietary restrictions, avoid with SSRIs and certain drugs |
| Aminoglycosides, Amphotericin B, ACE Inhibitors, NSAIDs | Renal Impairment |
| Beta Blockers, Calcium Channel Blockers, Digoxin | Cardiac Effects |
| Antipsychotics, SSRIs, MAO Inhibitors | Mental Health Side Effects |
| Statins, Methotrexate, Corticosteroids | Liver Function Concerns |
| Warfarin, Clopidogrel, NSAIDs | Increased Bleeding Risk |
Created by:
newty
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