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Opiods

TermDefinition
Morphine
Codeine
Hydromorphone (Dilaudid)
Hydrocodone/APAP (Vicodin, Lortab, Norco)
Oxycodone (OxyContin)
Levophanol (Levo-Dromoran)
Oxymorphone (Numorphan)
Apomorphone (Apokyn) Not an opiod agonist D1/D2 Dopamine Receptor agonist
Meperidine (Demerol) Short duration of action and less potent than morphine
Fentanyl (Sublimaze) Fentanyl Transdermal (Duragesic) Phenylpiperidine-like opioids - anesthetics More lipid soluble - higher onset - short duration less histamine release Intrathecal Administration - SPINE
Loperamide (Immodium) Diphenoxylate (Lomotil) Difenoxin (Immodium) Phenylpiperidine-like Opioids - Antidiarrheal agents Low abuse potential - low solubility and poor BBB penetration Non acting opioid
Methadone (Dolophine) Long duration of action Long-acting analgesia - occupies opioid receptors longer NMDA receptor antagonist : INC analgesia, DEC dependence
Tramadol (Ultram) Weak mu receptor agonist Inhibits NE and 5-HT uptake Effective morphine for mild to moderate pain Less respiratory suppression and constipation
Tapentadol (Nucynta) Mixed agonist-antagonist and partial agonist Weak analgesic effects Partial agonist activity at mu receptors Precipitate withdrawal from full agonist
Buprenophine (Buprenex ) Mixed Agonist-Antagonist and Partial Agonist Partial mu agonist; some kappa antagonist activity
Naloxone (Narcan) Opioid Antagonist Pure opioid antagonist, nonselective, short half life 90 min Antagonize endogenous opioid peptides Rescue Medication
Naltrexone (Revia) Opioid Antagonist Similar to Naloxone Longer Acting than Naloxone 1/2 life - 4 hrs : Used in Maintenance
Proteinoids (COX) Non-Opioid Analgesics Anti- Inflammatory
Leukotrienes (LOX) LTB4, LTC4, etc. Inflammation and Bronchoconstriction
Created by: kimi_neria
Popular Pharmacology sets

 

 



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