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Psychopharm-TermsE4
| Question | Answer |
|---|---|
| abuse | self-administration of any drug in a culturally disapproved manner that causes adverse consequences |
| addiction | a behavioral pattern of drug abuse characterized by overwhelming involvement with the use of a drug (compulsive use), the securing of its supply, and a high tendency to relapse after discontinuation |
| dependence | the physiological state of neuroadaptation produced by repeated administration of a drug, necessitating continued administration to prevent the appearance of the withdrawal syndrome |
| reinforcement | the tendency of a pleasure-producing drug to lead to repeated self-administration |
| tolerance | tolerance has developed when after repeated administration, a given dose of a drug produces a decreased effect, or conversely, when increasingly larger doses must be administered to obtain the effects observed with the original use |
| cross-tolerance and cross-dependence | the ability of one drug to suppress the manifestations of physical dependence produced by another drug and to maintain the physically dependent state |
| withdrawal | the psychologic and physiologic reactions to abrupt cessation of a dependence-producing drug |
| relapse | the reoccurrence on discontinuation of an effective medical treatment of the original condition from which the patient suffered |
| rebound | the exaggerated expression of the original condition sometimes experienced by patients immediately after cessation of an effective treatment |