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B Pharmaco Ex2

PCOL Adrenergic Drug/ Extra Key Info

DrugExtra/ Key Info
Phenylephrine Nasal decongestant & Ophthalmics (Mydriasis) Down Regulation-->Rebound congestion Avoid HTN patients
Cocaine Used with Lidocaine to control Arrhythmias (Na+ channel blocker)
Dextroamphetamine/Amphetamine (Addy) Methylphenidate (Concerta, Ritalin) Lisdexamphetamine (Vyvanse) Dexmethylphenidate (Focalin) ADHD
Phenelzine Inhibits breakdown of NE Serious ADR--> HTN crisis due to dietary Tyramine
Selegiline Rasagiline Inhibits breakdown of NE Used for Depression & Parkinson's
Prazosin Terazosin (Hytrin) Doxazosin (Cardura) Tamsulosin (Flomax) -> alpha1a Treat HTN, BPH, & PTSD (only on of the drugs) Decrease Preload and Afterload (blood vessels)
Phenoxybenzamine Used for HTN Crisis caused by Phenelzine (short term control) Longer duration of action (irreversible-->highest affinity for a1)
Mirtazapine (Remeron) Used for MDD Rare side effect: Agranulocytosis a2's are located in small blood vessels and cause vasoconstriction-->antagonist will cause vasodilation-->Peripheral edema
Clonidine (Catapres) Brimonidine (Alphagan P) Tizanidine (Zanaflex) Guanfacine (Intuniv) Dexmedetomidine (Precedex) HTN Crisis can occur if taken off drug abruptly due to Up-Regulation of receptors.
Created by: teregarci7
Popular Pharmacology sets

 

 



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