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B Pharmaco Ex2

PCOL Neuromuscular Drug/Extra Key Info

DrugExtra/Key Info
Acetylcholine Diarrhea, Urination, Miosis, Bradycardia, Broncho constriction, Emesis, Lacrimation, Salivation, Stimulation (CNS)
Varenicline (Chantix) FDA warning of mood/behavioral changes; used for smoking cessation
Succinylcholine Phase 1: binds to ACH space and keeps all Na+ channels open (cannot repolarize) Phase 2: blocks Na+ channels (cannot depolarize)
Physostigmine Penetrates CNS/ Cross BBB Treatment for Anti-Muscurinic Poisoning (Atropine)
Donepezil (Aricept) Rivastigmine (Exelon) Galantamine Lipophilic/Cross BBB Used for Dementia/Alzheimer's Longer t1/2 life than Physostigmine
PyriDOstigmine Neostigmine DO NOT CROSS BBB Reverse the effects of Curare Treatment for Myasthenia Gravis
Edrophonium Used for diagnosis of Myasthenia Gravis or Medication dose adjustment Short duration of action/ Reversible
Echothiophate Ophthamology treatment of Glaucoma
Botulinum Toxin (Botox) Cleaves sites on SNARE protein
Mivacurium Vecuronium Rocuronium Pancuronium Tubocurarine Doesn't allow ACH to binds; ACH is require for muscle contraction
Created by: teregarci7
Popular Pharmacology sets

 

 



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