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Opthalmic RX
| Question | Answer |
|---|---|
| Types of opthalmic agents? (5) | 1. antiglaucoma; 2. anti-infectives; 3. anti-inflammatories; 4. topical anesthetics; 5. miscellaneous agents; |
| Types of antiglaucoma agents? (5) | 1. parasympathomimetics (mitotics); 2. Sympathomimetics (Mydriatics); 3. Beta Adrenergic Agents; 4. Carbonic Anhydrase Inhibitors; 5. Osmotic Diurectics; |
| Effects of Miotics on the pupil? | contriction |
| effects of Mydriatics on the pupil? | dilation |
| Miotic drugs? (3) | Acetylcholine (Miochol), Pilocarpine (Ocuset), & Physostigimine (Isopto Eserine); |
| Important things to remember about Acetylcholine (Miochol)? | quick onset, used t produce mitot during surgery (constriciton) |
| Important things to remember about Pilocarpine (Ocuset)? | used in tx of glaucoma; available in occular preparation which may only need to be given once a week; excellent for non-compliant pt's |
| Important things to remember about Physostigmine (Isopto Eserine)? | inhibits the breackdown of acetlycholine; contraindicated in those with acute inflammation of the iris or ciliary body; |
| Important things to remember about Apraclonidine (Iopidine)? | Mydriatic (dilation, primarily used to inhibit intraoperative increase in IOP; |
| Important things to remember about Dipvefrin (Propine)? | Mydriatic (dilation); a prodrug of epinephrine; |
| Important things to remember about Betaxolol (Betopic)? | beta adrenergic blocker; excellent agent for use in open angle glaucoma and ocular hypertension; |
| Important things to remember about Acetazolamide (Diamox)? | Carbonic anyhydrase inhibitor; primarily used in tx of glaucoma also used as an adjunct anticonvulsant; used in tx of mountain sickness; |
| Important things to remember about Glycerin (Osmoglyn)? | osmotic diuretic; can be used pre and pos op to reduce IOP; available orally; |
| Important things to remember about Mannitol (Osmitrol)? | osmotic diuretic; used to reduce IOP that can not be reduced by other means; preoperatively used in ocular surgery, available in 5, 10, 20, and 25% parenteral solutions; |
| Important things to remember about Natamycin? | anti-infective, antifungal agent, can cause a visual haze and temporary overgrowth of non-susceptible organisms; |
| Important things to remember about Bacitracin? | anti-infective; available in combinaion with neomycin or polymixin; prefered to nemycin because fewer organisms are resistant to it; |
| Important things to remember about Cloraphenicol (Choloromycetin)? | anti-infective; most commone side effect is stinging and buring upon instilation; |
| Important things to remember about Silver Nitrate? | anti-infective; antiseptic, germacidal for a long time used on newborns to prevent gonorrheal infections; now eiter topical erythromyin or tetracycline can be used for this; |
| Important things to remember about Vidarabin (Vira A)? | anti-viral; tx of herpes simplex, kreatitis & keratoconjunctivitis; has the broadest antiviral spectrum; |
| Important things to remember about Flubiprofen (Ocufen)? | anti-inflammatory; NSAID often used post op after cataract extraction; |
| Important things to remember about Ketotolac (Acilar)? | anti-inflammatory; only parenteral NSAID that can be given either IM or IV; opthalmic topical is used to reduce inflammation of trauma, allergens, and bacteria; |
| Types of Otic Agents? (6) | 1. Antibiotics; 2. antibiotic & steroid combinations; 3. ntifungals; 4. wax emulsifiers; 5. local anesthetics; 6. local analgesics; |
| Important things to remember about Chloramphenicol (Choloromycetin OTC)? | antibiotic; broad spectrum of activity; can produce buring, redness, rash and swelling when applied topically; contraindicated in presence of eardrum perforation; |
| Important things to remember about Benzocaine (ingrediant in allergen ear drops, Auralgan Otic)? | Local anesthetic; used in combination with analgesics and emollients for relief of pain itching or burning; |
| Important things to remember about Carbamide Peroxide (ingredient in Debrox DRops, Murine Ear Drops)? | wax emulsifier; combined with other agents such as glycerol; source of hydrogen peroxide which is slowly released and acts as a weak antibacterial and effervescence which losens ear wax; |
| Pt teaching for instillation of ear drops? (7) | 1. do not touch dropper to the ear; 2. may cause dizziness upon intillation so instill lying down; 3. apply drops @ room temp or warm under hot water; 4. in children 3+ and adults hold pinna up and back; 5. in children 3- pull pinna down & back; |
| Pt teaching for instillation of ear drops? (7)cont. | cont. 6. lie on the side opposite the affected ear for 5 minutes after instillation; 7. ear drops are contraindicated when the tempanic membrane is perforated |