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Dermatological RX
| Question | Answer |
|---|---|
| Functions of the skin r/t internal organs? | serves as a protective barrier to internal organs; |
| Functions of the skin r/t growth of microoganisms? | maintains a protective pH of 4.5-5.5; the wealy acidic environment discourages growth of microorganisms because the prefer a pH of 6.6-7.5; |
| Functions of the skin r/t temperature, pain, and pressure? | serves as a sensor |
| Functions of the skin r/t temerpature? | plays a major role in temp. regulation; heat loss and heat conservation regulated through perspiration & adjustments in capillary caliber; |
| Functions of the skin r/t electolytes? | excretes fluids and electrolytes through sewat glands; |
| Functions of the skin r/t fats & vitamins? | stores fat and synthesizes vitamin D |
| Functions of the skin r/t drugs? | provides a site for drug absorption |
| What is the most penetrating type of dermatological preperation? | ointments |
| When is Bacitracin (Baciguent) normally used? | used for tx of infection by susceptible aerobic and anaerobic gram positive organisms and in combination with other agents to expand it's spectrum; |
| Classification, MOA, and therapeutic use of Erythromycin (A/T/S)? | antibiotic; bacteriostatic but my be bacteriocidal in high concentrations for susceptible organisms; used for topical tx of acne vulgaris, a common form of acne; |
| Advers rxn of Erythromycin (A/T/S)? | erythema, desquamation, tenderness, dryness, pruritis, oiliness |
| Pt teaching for Erythromycin (A/T/S)? (2) | 1. apply BID to cleansed skin; 2. avoid cleansing with abrasive agents prior to use; |
| Classification and therapeutic use of Miconazole (Monistat, Mica Tin)? | antifungal ingredient found in OTC preperations used for tx of vulvovaginal candida, athletes foot, jock itch, ringworm; |
| Advers rxn of Miconazole (Monistat, Mica Tin)? | vulvovaginal burning, pelvic cramps, rash, uticaria, stinging, buring, contact dermatitis; |
| Pt teaching for Miconazole (Monistat, Mica Tin)? | apply BID to Cleansed skin |
| Classification and therapeutic use of Acyclovir? | antiviral applied topically for tx of recurrent herpes simplex infections in immunocomprimised hosts; prevention and tx of these infections are more effectively treated systematically but topica acyclovir does decrease the healing time and associated pain |
| Adverse rxn of Acyclovir? | stinging, burning, rash |
| Administration of Acyclovir? | availiable in ointment that is applied 6x daily for 1 week; a finger cot or glove should be worn when applying the agent to prevent spread of infection; |
| Classification and Therapeutic use of Lindane (Kwell)? | ecoparasiticidal agent used to treat lice and scabies; |
| Adverse rxn of Lindane (Kwell)? | skin rash, rarely CNS toxicity in young children; |
| Administration of Lindane (Kwell)? | for body of pubic lice, applied and left on 12 hours, then washed off; head lice are treated with a shampoo that is left in four minutes before rinsing; for scabies, lindane is applied all over the body, left on 8-12 hours, then rinsed off; |
| MOA and therapeutic use of Minoxidil (Rogaine)? | vasodilating drug used systemically for hypertension, used locally to promote hair growth; |
| Adverse rxn of Minoxidil (Rogaine)? | r/t systemica absorption of the drug: tachycardia, fluid retention, weight gain; |
| Administration of Minoxidil (Rogaine)? | apply to the area BID, may take 4 months to see results; |
| Classification and therapeutic use of Flourouracil (Efudex)? | antineplastic that treats solar or actinic keratosis and bassal cell carcinomas when surgical resection is not feasible; |
| Adverse rxn of Flourouracil (Efudex)? | local inflammatory reactions, dermatitis, stomatitis, photosensitivity, swelling, pain scaling, suppuration, scaring and hyperpigmentation; |
| Administration of Flourouracil (Efudex)? | should be applied with non metal applicator or with clean gloved fingertips, fingers should be washed thoroughly after touching' |
| Classification, MOA and therapeutic use of Silver Sulfadiazine (Silvadene)? | topical burn drug that forms protective mildly anti-infective barrier on skin used in tx and prevention of infections in second and thrid degree burns; |
| Adverse rxn of Silver Sulfadiazine (Silvadene)? | pain, burning, itching |
| Adminitration of Silver Sulfadiazine (Silvadene)? | apply with sterile glove once or twice after the area has been cleansed and debrided; |