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Musculoskeletal

GenericBrandPharmacologic CategoryCommon IndicationsClassificationEssential Knowledge
tizanidine (PO) Zanaflex Alpha2 agonist Spasticity Key Side Effects: drowsiness, hypotension, dizziness, xerostomia, weakness
hydroxychloroquine (PO) Plaquenil Aminoquinolone RA, SLE, malaria Key Side Effects: retinal toxicity, rash, diarrhea
colchicine (PO) Colcrys Antigout agent Gout Key Side Effects: diarrhea, nausea, vomiting, bone marrow suppression, myopathy (including rhabdomyolysis)
diclofenac (PO) Voltaren NSAID OA, RA, acute pain Key Side Effects: diarrhea, dyspepsia, abdominal pain, flatulence, nausea US Boxed Warnings: increase risk of serious/fatal cardio thrombotic events, MI, and stroke; increase risk for serious/fatal GI adverse events (bleeding, ulceration, perforation)
ibuprofen (PO) Motrin, Advil NSAID OA, RA, acute pain OTC Key Side Effects: diarrhea, dyspepsia, abdominal pain, flatulence, nausea US Boxed Warnings: increase risk of serious/fatal cardio thrombotic events, MI, and stroke; increase risk for serious/fatal GI adverse events (bleeding, ulceration, perforation)
meloxicam (PO) Mobic NSAID OA, RA, acute pain Key Side Effects: diarrhea, dyspepsia, abdominal pain, flatulence, nausea US Boxed Warnings: increase risk of serious/fatal cardio thrombotic events, MI, and stroke; increase risk for serious/fatal GI adverse events (bleeding, ulceration, perforation)
indomethacin (PO) Indocin NSAID OA, RA, acute pain, gout Key Side Effects: diarrhea, dyspepsia, abdominal pain, flatulence, nausea US Boxed Warnings: increase risk of serious/fatal cardio thrombotic events, MI, and stroke; increase risk for serious/fatal GI adverse events (bleeding, ulceration, perforation)
naproxen (PO) Naprosyn, Anaprox, Aleve NSAID OA, RA, acute pain, gout OTC Key Side Effects: diarrhea, dyspepsia, abdominal pain, flatulence, nausea US Boxed Warnings: increase risk of serious/fatal cardio thrombotic events, MI, and stroke; increase risk for serious/fatal GI adverse events (bleeding, ulceration, perforation)
ketorolac (PO, IV) Toradol NSAID Pain Key Side Effects: diarrhea, dyspepsia, abdominal pain, flatulence, nausea US Boxed Warnings: indicated for short term use (</=5 days)
celecoxib (PO) Celebrex NSAID, COX-2 selective OA, RA, acute pain Key Side Effects: diarrhea, dyspepsia, abdominal pain, flatulence, nausea US Boxed Warnings: increase risk of serious/fatal cardio thrombotic events, MI, and stroke; increase risk for serious/fatal GI adverse events (bleeding, ulceration, perforation)
diclofenac (topical) Voltaren Gel NSAID OA OTC Key Side Effects: pruritus, rash
cyclobenzaprine (PO) Flexeril, Amrix, Fexmid Skeletal muscle relaxant Muscle spasm Key Side Effects: drowsiness, dizziness, xerostomia, fatigue
baclofen (PO) --- Skeletal muscle relaxant Spasticity Key Side Effects: drowsiness
methocarbamol (PO) Robaxin Skeletal muscle relaxant Muscle spasm Key Side Effects: drowsiness
lidocaine (transdermal, IV) Transdermal: Lidoderm, IV: xylocaine Transdermal: topical analgesic IV: antiarrhythmic Transdermal: pain, IV: ventricular arrhythmias Transdermal: OTC Key Side Effects (Transdermal): dermatitis, erythema, urticaria, skin depigmentation, skin edema. Key side Effects (IV): bradycardia
allopurinol (PO) Zyloprim Xanthine oxidase Inhibitor Gout Key Side Effects: diarrhea, nausea, rash, leukopenia, thrombocytopenia
SuccinylCholine (IV) Anectine Depolarizing neuromuscular blocking agent Neuromuscular blockade for intubation or procedures Key Side Effects: hyperkalemia, myalgia, malignant hyperthermia (rare). US Boxed Warnings: acute rhabdomyolysis and hyperkalemia leading to cardiac arrest and death in pediatric patients w/ undiagnosed skeletal muscle disease.
Etanercept (PO) Enbrel Anti-tumor necrosis factor alpha inhibitor RA Key Side Effects: infection, injection site reaction, headache, nausea US Boxed Warnings: serious infections, malignancies such as lymphoma
Adalimumab (SQ) Humira Anti-tumor necrosis factor alpha inhibitor RA, Crohn's Disease, Ulcerative Colitis Key Side Effects: infection, injection site reaction, headache, nausea US Boxed Warnings: serious infections, malignancies such as lymphoma
Created by: Kateloki
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