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Neuro/Psych 4 & 5

GenericBrandPharmacologic CategoryCommon IndicationsClassificationEssential Knowledge
carbamazepine (PO) Tegretol Anticonvulsant Seizure disorders, bipolar disorder Key Side Effects: dizziness, drowsiness, headache, ataxia, nausea, vomiting, hyponatremia. US Boxed Warnings: risk of dermatologic reactions (including SJS + TEN) in patients w/ certain genetic predisposition; may cause aplastic anemia + agranulocytosis
Lamotrigine (PO) Lamictal Anticonvulsant Seizure disorders, bipolar disorder Key Side Effects: nausea, vomiting, somnolence, skin rash, alopecia. US Boxed Warnings: risk of serious dermatologic reactions, including SJS.
divalproex (valproic acid derivative) (PO) Depakote, Depakote ER Anticonvulsant Seizure disorders, bipolar disorders, migraine prophylaxis Key Side Effects: drowsiness, weight gain, tremor, alopecia, thrombocytopenia, hyperammonemia. US Boxed Warnings: may cause fatal hepatic failure; may cause life threatening pancreatitis; fetal toxicity
topiramate (PO) Topamax Anticonvulsant Seizure disorders, migraine prophylaxis Key Side effects: somnolence, dizziness, memory impairment, weight loss.
levetiracetam (PO, IV) Keppra Anticonvulsant Seizure disorders Key Side Effects: somnolence, dizziness, nausea, vomiting, weakness, asthenia, psychotic symptoms, agitation.
oxcarbazepine (PO) Trileptal Anticonvulsant Seizure disorders Key Side Effects: somnolence, dizziness, diplopia, nausea, vomiting, ataxia, hyponatremia.
gabapentin ( PO) Neurontin Anticonvulsant Seizure disorders, neuropathic pain Key Side Effects: somnolence, dizziness, ataxia, fatigue, diplopia, xerostomia, blurry vision, peripheral edema, weight gain.
Pregabalin (PO) Lyrica Anticonvulsant Seizure disorders, neuropathic pain CS-V Key Side Effects: somnolence, dizziness, ataxia, fatigue, diplopia, xerostomia, blurry vision, peripheral edema, weight gain.
buspirone (PO) Buspar Antianxiety agent Anxiety Key Side Effects: dizziness, drowsiness, nausea
alprazolam (PO) Xanax Benzodiazepine Anxiety CS-IV Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal, dizziness, ataxia. Boxed: risk of profound sedation, respiratory depression, coma, death w/ opioids, abuse, misuse, addiction, withdrawal rxns
Clonazepam (PO) Klonopin Benzodiazepine Anxiety, seizure disorders CS-IV Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal, dizziness, ataxia. Boxed: risk of profound sedation, respiratory depression, coma, death w/ opioids, abuse, misuse, addiction, withdrawal rxns
diazepam (PO, IV) Valium Benzodiazepine Anxiety, seizure disorders, acute alcohol withdrawal CS-IV Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal, dizziness, ataxia. Boxed: risk of profound sedation, respiratory depression, coma, death w/ opioids, abuse, misuse, addiction, withdrawal rxns
lorazeram (PO, IV) Ativan Benzodiazepine Anxiety, seizure disorders, acute alcohol withdrawal CS-IV Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal, dizziness, ataxia. Boxed: risk of profound sedation, respiratory depression, coma, death w/ opioids, abuse, misuse, addiction, withdrawal rxns
midazolam (IV, IM) Versed Benzodiazepine Anesthesia, sedation CS-IV Effects: hypotension, apnea, bradypnea. Boxed: risk of profound sedation,respiratory depression, coma,death w/ opioids, abuse, misuse, addiction, dependence, withdrawal rxns, sedation in noncritical settings, dose individualized, no rapid inj. in neonates
zolpidem (PO) PO: Ambien, Ambien CR SL: Edluar Hypnotic Insomnia CS-IV Effects: decreased ability to function the next morning, somnolence, headache, dizziness, xerostomia, anterograde amnesia, parasomnias. Boxed: serious injuries, including death have occurred bc of complex sleep behaviors; CI in patients w/ sleep behavior
propofol (IV) Diprivan Sedative, general anesthetic Sedation for mechanical ventilation , procedural anesthesia, status epilepticus Key Side Effects: bradycardia, hypotension, hypertriglyceridemia, propofol-related infusion syndrome (rare)
dexmedetomidine (IV) precedex Alpha 2 agonist, sedative Sedation for mechanical ventilation or procedures Key Side Effects: bradycardia, hypotension
melatonin (PO) --- Sleep aid Insomnia, jet lag OTC Key Side Effects: drowsiness, daytime somnolence
Created by: Kateloki
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