Save
Busy. Please wait.
Log in with Clever
or

show password
Forgot Password?

Don't have an account?  Sign up 
Sign up using Clever
or

Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Ch 21 Cancer

Antineoplastic Agents

QuestionAnswer
What are the 5 phases of the cell cycle? first growth phase (G1), synthesis (S1), second growth phase (G2), mitosis (M), and resting phase (G0)
How are agents most commonly given? In combinations of 2 or more at a time
How do Antimetabolites prevent cancer cell growth? By affecting DNA production
What are 7 therapeutic uses of the Antimetabolite Methotrexate (MTX)? Used for acute lymphoblastic leukemia, meningeal leukemia, head and neck cancers, rheumatoid arthritis, psoriasis, ectopic pregnancy, and inflammatory bowel disease.
What are 3 drug interactions with the Antimetabolite Methotrexate (MTX)? Avoid alcohol, aspirin, NSAIDs
What are hormonal agents? A class of heterogenous compounds that have various effects on cells.
How do hormonal agents work? They either block hormone production or block hormone action.
Hormonal agents' action on malignant cells is _________ selective. They are the _____________ toxic of the anticancer medications. highly, least
What Antitumor Antibiotic is the single most active agent against breast cancer? Doxorubicin
What are the adverse effects of the Antitumor Antibiotic Doxorubicin? Serious, irreversible myocardial toxicity, hypertension, and hypotension
Describe the Antitumor Plicamycin? A cytotoxic, antibiotic, and antineoplastic agent
What is the mechanism of action for the Antitumor Plicamycin? Appears to block the hypercalcemic action of vitamin D and may inhibit the effect of parathyroid hormone on bone cells (osteoclasts)
What are the adverse effects of the Alkylating Agent Cyclophosphamide, including long-term toxicity? anorexia, vomiting, alopecia (hair loss), leukopenia, and potentially serious hemorrhagic cystitis. Long-term toxicity includes sterility and carcinogenesis.
How is the Alkylating Agent Melphalan well absorbed? Orally
What is the major use for the Alkylating Agent Melphalan? The treatment of multiple myeloma (a special cancer of the white blood cells that causes abnormal plasma cells to develop)
The Alkylating Agent Melphalan is usually used in combination with: Prednisone
What are other two uses for the Alkylating Agent Melphalan? breast cancer and melanoma
This is a Mitotic Inhibitor (Plant Alkaloid) and antineoplastic agent: Etiposide
What is the major use for the Mitotic Inhibitor (Plant Alkaloid) Etiposode? Treatment of refractory testicular tumors as part of combination therapy.
Immunosuppression has what harmful effects? Makes the patient more vulnerable to infection.
About _____% of patients with cancer die of intercurrent infections rather than from terminal phases of cancer. 50%
Created by: 1531944093
Popular Pharmacology sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards