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Orange Block 3,4,&5
| Question | Answer |
|---|---|
| Commonly used to treat Type 2 Diabetes Mellitus Ends is -glitazone | Thiazolidinediones |
| Know as Oral anti-diabetic | Thiazolidinediones |
| Increases tissue sensitivity to insulin | MOA of Thiazolidinediones |
| N/V/D Weight gain Liver failure Heart Failure | Common Adverse Reactions of Thiazolidinediones |
| pioglitazone | Actos |
| 15mg, 30mg, 45mg tabs | Actos |
| rosiglitazone | Avandia |
| 2mg, 4mg, 8mg tabs Available in combination with Metformin | Avandia |
| Commonly used to treat Type 2 Diabetes Mellitus ends in -tide | Incretin Mimetics GLP-1 Agonist |
| Stimulates GLP-1 receptors in alpha & beta cells in pancreas * beta cell stimulation mediates insulin secretion when glucose levels increase | MOA of Incretin Mimetics GLP-1 Agonist |
| Delays gastric emptying by causing decreased appetite, and slows the rise of post-prandial blood glucose levels. | MOA of Incretin Mimetics GLP-1 Agonist |
| exenatide | Byetta |
| SQ injection Inject 60 mins before morning and evening meal | Byetta |
| liraglutide | Victoza |
| SQ injection Store in refrigerator Pen stable fro 30 days after opening | Victoza |
| Commonly used to treat Hypothyroidism (low thyroid) | Thyroid Replacements |
| Supplementation of thyroid hormone | Thyroid Replacements |
| Has more rapid onset of action & shorter duration of action | T3 |
| Has longer onset of action & longer duration of action | T4 |
| Why must you keep patients on same brand of thyroid replacements? | Different manufacturers has different bioavailability |
| Interferes with the absorption of thyroid food delays with absorption | Iron and Calcium |
| Take on empty stomach Take with water | Common Auxiliary labels for Thyroid Replacements |
| 1 tablet once daily, usually first thing in the morning | Common doses for Thyroid Replacements |
| levothyroxine | Eltroxin & Synthroid |
| 50mcg, 100mcg, 150mcg, 200mcg, 300mcg tabs | Eltroxin |
| 25mcg, 50mcg, 75mcg, 88mcg, 100mcg, 112mcg, 125mcg, 137mcg, 150mcg, 175mcg, 200mcg, 300mcg tabs | Synthroid |
| dessicated thyroid | Armour |
| 30mg, 60mg, 125mg tabs | Armour |
| liothyronine | Cytomel |
| 5mcg, 25mcg tabs | Cytomel |
| Commonly used to treat Hyperthyroidism | Thioamides |
| Inhibits conversion of T4 to T3 | MOA of Tapazole (methimazole) |
| Inhibits synthesis of thyroid hormones | MOA of Propyl-Thyracil (propylthiouracil) |
| methimazole | Tapazole |
| 5mg, 10mg tabs | Tapazole |
| propylthiouracil | Propyl-Thyracil |
| 50mg, 100mg tabs | Propyl-Thyracil |
| Commonly used to treat BPH Ends in -osin | Alpha blockers Alpha Adrenergic Antagonists |
| Binds tp receptor sites Blocks vasoconstriction Relaxes prostate and bladder smooth muscles Reduces urethral resistance Improves urine flow | MOA of Alpha Blockers |
| Postural hypotension, dizziness, weakness, fatigue, and tachycardia | Common Adverse Reactions of Alpha Blockers |
| Commonly dosed once daily | Alpha Blockers |
| doxazosin | Cardura |
| 1mg, 2mg, 4mg tabs | Cardura |
| tamulosin | Flomax |
| 0.4mg caps and tabs Extended release Swallow whole, do not crush or chew | Flomax |
| terazosin | Hytrin |
| 1mg, 2mg, 5mg, 10mg tabs | Hytrin |
| silodosin | Rapaflo |
| 4mg, 8mg tabs | Rapaflo |
| alfuzosin | Xatral |
| 10mg tabs | Xatral |
| Commonly used to treat BPH ends in -asteride | 5-alpha Reductase Inhibitors |
| Inhibits the action of 5a reductase increased testosterone levels are associated with excess growth of prostate tissue. | MOA of 5-alpha Reductase Inhibitors |
| Harmful to developing fetus Avoid handling with crushed or broken tabs | 5-alpha Reductase Inhibitors |
| Erectile Dysfunction | Common Adverse Reaction of 5-alpha Reductase Inhibitors |
| dutasteride | Avodart |
| 0.5mg caps | Avodart |
| finasteride | Proscar |
| 5mg tabs 1mg tabs, Propecia ( used to treat hair loss) | Proscar |
| Commonly used to treat Erectile Dysfunction | Phosphodiesterase Inhibitors |
| Relaxes smooth muscles & blood vessels controlling penile enlargement Increases nitric oxide levels | MOA of Phosphodiesterase Inhibitors |
| Flushing, dizziness, headache, and visual effects | Common Adverse reactions of Phosphodiesterase Inhibitors |
| Life threatning drop in blood pressure if taken with nitrates Use cautions when taking alpha antagonists, anti-fungals, and macrolide ABX | Adverse Reactions of Phosphodiesterase Inhibitors |
| Avoid grapefruit Avoid nitrates | Common Auxiliary Labels of Phosphodiesterase Inhibitors |
| tadalafil | Cialis |
| 2.5mg, 5mg, 10mg, 20mg tabs | Cialis |
| vardenafil | Levitra |
| 5mg, 10mg, 20mg tabs | Levitra |
| sildenafil | Viagra |
| 25mg, 50mg, 100mg tabs | Viagra |
| Used to treat pulmonary hypertension | Revatio (sildenafil) |
| Commonly used to treat GERD and Acid Reflux ends in -tidine | Histamine 2 Receptors Antagonists H2 Antagonists |
| Competitively binds to histamine2 receptors Blocks acid secretion | MOA of H2 Antagonists |
| nizatidine | Axid |
| 150mg, 300mg caps and tabs | Axid |
| famotidine | Pepcid |
| 10mg, 20mg, 40mg tabs 10mg & 20mg tabs available OTC | Pepcid |
| cimetidine | Tagamet |
| 200mg, 300mg, 400mg, 600mg, 800mg tabs | Tagamet |
| ranitidine | Zantac |
| 75mg, 150mg, 300mg tabs Often dosed BID 75mg available OTC | Zantac |
| Commonly used to treat GERD and Acid Reflux ends in -prazole | Proton Pump Inhibitors PPIs |
| Decreases levels of gastric acid by interfering with final step in production of gastric acid Inhibits the proton pump | MOA of Proton Pump Inhibitors |
| Often dosed 1-2 times daily | Proton Pump Inhibitors |
| dexlansoprazole | Dexilant |
| Delayed release capsules - 30mg, 60mg | Dexilant |
| omeprazole | Losec |
| 10mg, 20mg, 40mg caps and tabs | Losec |
| esomeprazole | Nexium |
| 20mg, 40mg tabs | Nexium |
| pantoprazole sodium | Pantoloc |
| 20mg, 40mg tabs | Pantoloc |
| rabeprazole | Pariet |
| 10mg, 20mg tabs | Pariet |
| lansoprazole | Prevacid |
| 15mg, 30mg caps and fast tabs | Prevacid |
| pantoprazole magnesium | Tecta |
| 40mg tabs | Tecta |
| Commonly used to treat Ulcers, GERD, and Acid Reflux | Mucosal Protectants |
| misoprostol | Cytotec |
| Synthetic prostaglandin Stimulates production of protective mucus and bicarbonates in stomach Increases regeneration of gastric epithelial cells | MOA of Cytotec |
| Avoid use in pregnancy Stimulates uterine contractions | Common Adcerse reactions of Cytotec |
| 100mcg, 200mcg tabs Can be dosed up to 800mcg per day Often BID-QID | misoprostol |
| Take with food Avoid antacids containing magnesium | Common Auxiliary Labels for misoprostol |
| sulcrafate | Sulcrate |
| Binds to ulcer and from protective barrier Promotes regeneration of stomach epithelial cells | MOA of Sulcrate |
| 1g tabs Commonly dosed 1g QID or 2g BID 1 hr prior to meals | sulcrafate |
| Take on an empty stomach | Common Auxiliary Label for Sulcrate |
Created by:
Mhouff
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