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Neuro/Psych 3
| Generic | Brand | Pharmacologic Category | Common Indications | Classification | Essential Knowledge |
|---|---|---|---|---|---|
| lithium ( PO) | Lithobid | Antimanic agent | Bipolar disorder | Key Side Effects: tremor, acne, hypothyroidism, weight gain, polyuria, polydipsia, GI upset. US Boxed Warnings: ability to promptly monitor levels is necessary. | |
| sumatriptan (PO, intranasal, SQ) | Imitrex | Antimigraine | Migraine | Key Side Effects: fatigue, somnolence, dizziness, chest tightness, paresthesias | |
| haloperidol ( PO, IV, IM) | Haldol | First generation antipsychotic | Schizophrenia | Key Side Effects: sedation, EPS, parkinsonism, xerostomia, orthostatic hypotension, weight gain, QTc prolongation. US Boxed Warnings: elderly patients w/ dementia-related psychosis treated w/ antipsychotic drugs at increased risk of death | |
| clozapine (PO) | Clozaril | Second-generation antipsychotic | Treatment-resistant schizophrenia | Key Side Effects: sedation, constipation, orthostatic hypotension, sialorrhea, hyperglycemia, weight gain, neutropenia. US Boxed Warnings: may cause severe neutropenia; may cause orthostatic hypotension, bradycardia, syncope; seizures, fatal myocarditis, | |
| aripiprazole (PO, IM) | PO/IM: Abilify IM: Aristada | Second-generation antipsychotic | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) | Key Side Effects: akathisia, restlessness, sedation, EPS, constipation, orthostatic hypotension, weight gain. US Boxed Warnings: antidepressants increase the risk of suicidal thinking and behavior in children, adolescents and young adults; elderly | |
| quetiapine (PO) | Seroquel, Seroquel XR | Second-generation antipsychotic | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) | Key Side Effects: sedation, EPS, constipation, orthostatic hypotension, weight gain. US Boxed Warnings: antidepressants increase risk of suicidal thinking and behavior in children, adolescents and young adults; elderly patients w/ dementia-related psycho | |
| olanzapine (PO, IM) | Zyprexa | Second-generation antipsychotic | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) | Key Side Effects: sedation, EPS, xerostomia, constipation, orthostatic hypotension, weight gain, hyperglycemia. US Boxed Warnings: elderly patients w/ dementia-related psychosis treated w/ antipsychotic drugs at increased risk of death | |
| risperidone (PO, IM) | PO: Risperdal, IM: Risperdal Consta | Second-generation antipsychotic | Schizophrenia | Key Side Effects: sedation, EPS, xerostomia, constipation, orthostatic hypotension, weight gain, hyperglycemia. US Boxed Warnings: elderly patients w/ dementia-related psychosis treated w/ antipsychotic drugs at increased risk of death | |
| rizatriptan (PO) | Maxalt | Antimigraine | Migraine | Key Side Effects: fatigue, somnolence, dizziness, chest tightness, paresthesias | |
| lurasidone (PO) | Latuda | Second-generation antipsychotic | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) | Key Side Effects: sedation, EPS, constipation, orthostatic hypotension, weight gain. US Boxed Warnings: antidepressants increase risk of suicidal thinking/ behavior in children, adolescents/ young adults; elderly patients w/ dementia-related psychosis |