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PHARMA
PHARMA FUNDAMENTALS
| Question | Answer |
|---|---|
| "Pharmakon" | DRUGS |
| "Logos" | STUDY |
| PHARMACOLOGY | A branch of science that dealswith the study of drugs andtheir actions on living systems -that is, the study of how drugswork in the body (sometimesreferred to as 'drug actions’).(DOH) |
| The clinical purpose or indication for giving a drug. | PHARMACOTHERAPEUTICS |
| Deals with therapeutic uses of drugs. | PHARMACOTHERAPEUTICS |
| Body Action ----> DRUG | PHARMACODYNAMICS |
| Drug Action -----> BODY | PHARMACOKINETICS |
| A.D.M.E | Absorption, Distribution, Metabolism Excretion |
| Transmission of medications from the local administrations to the blood stream. | ABSORPTION |
| Determines how soon the medication will take effect. R__ OF M__ A___ | RATE OF MEDICATION ABSORPTION |
| The amount of medication absorbed determines it I___ | INTENSITY |
| The route of administration affects R___ and A_____ OF A_____ | THE RATE AND AMOUNT OF ABSORPTION |
| IV | INTRAVENOUS |
| IM | INTRAMUSCULAR |
| SQ | SUBCUTANEOUS |
| PO | PER ORAL |
| SL | SUBLINGUAL "UNDER THE TONGUE" |
| PI | PULMONARY INHALATION |
| T & T | TOPICAL & TRANSDERMAL |
| R | RECTAL |
| Transportation of medications to sites of actions by bodily fluids | DISTRIBUTION |
| Formed by Metabolism | METABOLITES |
| How the body converts medications into a less or more active forms. | METABOLISM |
| Factors Influencing Medication Metabolism - A.FPP.NS.SMP | AGE, FIRST PASS PHENOMENON, NUTRITIONAL STATUS, SIMILAR METABOLIC PATHWAYS |
| Eliminating medications from the body | Excretion |
| Refers to the period of time needed for the medication to be excreted in the body. H__-L___ | HALF - LIFE |
| Describes the interaction between medications and target cells, organs and body systems. | PHARMACODYNAMICS |
| Refers to biologic and therapeutic effects of drugs at the site of action or on the target organs. | PHARMACODYNAMICS |
| Deals with the physiological effects of the drug on the body. | PHARMACODYNAMICS |
| These interactions result in functional changes that are considered mechanism of actions of medications. | PHARMACODYNAMICS |
| Mimic the receptor activity regulated by endogenous compound. Example: Morphine Sulfate – activates receptors that produce analgesia. | AGONIST |
| Block normal receptor activity regulated by endogenous compound or receptor activity caused by other medications Example: Losartan – receptor blocker – blocks angiotensin II receptors on blood vessels which prevents vasoconstriction. | ANTAGONIST |
| May act as an agonist/ antagonist. Example: Nubian, acts as an antagonist at mu receptors and an agonist at kappa receptors, causing analgesia with minimal respiratory depression at low dosses. | PARTIAL AGONIST |
| Drugs that occupy receptors and activate them. | AGONISTS |
| Drugs that occupy receptors but do not activate them. Block receptor activation by Agonists. | ANTAGONISTS |
| 4 Major Targets - R.IC.E.T | RECEPTORS, ION CHANELS, ENZYMES, TRANSPORTERS |
| What organ eliminates medication from the body? | KIDNEY |
| What organ is responsible for metabolism? | LIVER |
| 5 Medical Administration - P.D.P.A.E | PRESCRIPTION, DISPENSING, PREPARATION, EVALUATION, ADMINISTRATION |
| Determined by Chemical Composition | CHEMICAL NAME |
| Official Name of the Medicine | GENERIC NAME |
| Trade name | Company/Manufacturer |
| Limited medication metabolizing capacity. | INFANT |
| Hepatic Medication metabolism tends to decline with age. | ELDERS |
| Organized according to action. M__ OF ___ | MECHANISM OF ACTION |
| Usually expected & inevitable when medicine is given. S__E___ | SIDE EFFECTS |
| Undesired, inadvertent & unexpected dangerous effects of medicine. A___ E___ | ADVERSE EFFECT |
| Undesired but avoidable. T___ E___ | TOXIC EFFECT |
| desirable and preferred and expected effect. T___ E___ | THERAPEUTIC EFFECT |
| Know to monitor therapeutic effects. N___ C____ | NURSING COMPLICATIONS |
Created by:
ailabajenting
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