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Anti-Inflammatory
Anti-Inflammatory and analgesics
| Term | Definition |
|---|---|
| Mechanism of action of NSAIDs | The inhibition of the enzyme cyclooxygenase (COX) |
| Potential risks of long-term NSAID use | Gastrointestinal bleeding |
| Contraindication of NSAID use | 3rd trimester of pregnancy, renal, and hepatic impairment |
| Contraindications of ketorolac | Children, renal disease, history of peptic ulcers |
| First line therapy of fever and pain in children | Acetaminophen |
| Contraindications of acetaminophen | Patients with hepatic disease |
| Mechanism of action of opioid analgesics | The activating opioids receptors (mu, delta, kappa) in the brain |
| Contraindications of opioid analgesics | Respiratory depression, head trauma, increased intracranial pressure |
| Antipyretics | Medications that reduce fever by acting on the body's temperature-regulating center |
| Prostanglandins | Chemical messengers that play a role in promoting pain, inflammation, and fever |