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Neuro5

Neuro5 Essential Knowledge

Generic/BrandSide effects
Buspirone/ Buspar (PO) Key Side Effects: dizziness, drowsiness, nausea.
Alprazolam/ Xanax (PO) Key Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal. US Boxed Warning: risk of profound sedation, respiratory depression, coma and death with opioids; risk of abuse, misuse, and addiction; risk of dependence and withdrawal reactions. Other Notes (lorazepam IV only): parenteral formulation contains propylene glycol and may be associated with toxicity if used ≥ 48 hours.
Clonazepam/ Klonopin (PO) Key Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal. US Boxed Warning: risk of profound sedation, respiratory depression, coma and death with opioids; risk of abuse, misuse, and addiction; risk of dependence and withdrawal reactions. Other Notes (lorazepam IV only): parenteral formulation contains propylene glycol and may be associated with toxicity if used ≥ 48 hours.
Diazepam/ Valium (PO, IV) Key Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal. US Boxed Warning: risk of profound sedation, respiratory depression, coma and death with opioids; risk of abuse, misuse, and addiction; risk of dependence and withdrawal reactions. Other Notes (lorazepam IV only): parenteral formulation contains propylene glycol and may be associated with toxicity if used ≥ 48 hours.
Lorazepam/ Ativan (PO, IV) Key Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal. US Boxed Warning: risk of profound sedation, respiratory depression, coma and death with opioids; risk of abuse, misuse, and addiction; risk of dependence and withdrawal reactions. Other Notes (lorazepam IV only): parenteral formulation contains propylene glycol and may be associated with toxicity if used ≥ 48 hours.
Midazolam/ Versed (IV, IM) Key Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal. US Boxed Warning: risk of profound sedation, respiratory depression, coma and death with opioids; risk of abuse, misuse, and addiction; risk of dependence and withdrawal reactions. Other Notes (lorazepam IV only): parenteral formulation contains propylene glycol and may be associated with toxicity if used ≥ 48 hours.
Temazepam/ Restoril (PO) Key Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal. US Boxed Warning: risk of profound sedation, respiratory depression, coma and death with opioids; risk of abuse, misuse, and addiction; risk of dependence and withdrawal reactions. Other Notes (lorazepam IV only): parenteral formulation contains propylene glycol and may be associated with toxicity if used ≥ 48 hours.
Eszopiclone/ Lunesta (PO) Key Side Effects: decreased ability to function the next morning, somnolence, headache, dizziness, xerostomia, dysgeusia. US Boxed Warning: serious injuries, including death, have occurred because of complex sleep behaviors (i.e., sleepwalking, sleep driving, and engaging in other activities while not fully awake); contraindicated in patients with history of complex sleep behaviors.
Zolpidem/ PO: Ambien, CR, SL: Intermezzo Key Side Effects: decreased ability to function the next morning, somnolence, headache, dizziness, xerostomia, anterograde amnesia. US Boxed Warning: serious injuries, including death, have occurred because of complex sleep behaviors (i.e., sleepwalking, sleep driving, and engaging in other activities while not fully awake); contraindicated in patients with history of complex sleep behaviors.
Propofol/ Diprivan (IV) Key Side Effects: hypotension, hypertriglyceridemia, propofol-related infusion syndrome (rare).
Dexmedetomidine/ Precedex (IV) Key Side Effects: bradycardia, hypotension.
Created by: teregarci7
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