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Neuro4
Neuro4 Essential Knowledge
| Generic/Brand | Side effects |
|---|---|
| Carbamazepine/ Tegretol (PO) | Key Side Effects: dizziness, drowsiness, headache, ataxia, nausea, vomiting, hyponatremia. US Boxed Warnings: risk of serious dermatologic reactions (including SJS and TEN) in patients with certain genetic predisposition; may cause aplastic anemia and agranulocytosis. |
| Lamotrigine/ Lamictal (PO) | Key Side Effects: nausea, vomiting, somnolence, skin rash. US Boxed Warnings: risk of serious dermatologic reactions, including Stevens-Johnson syndrome (SJS). |
| Divalproex/ Depakote, Depakote ER, Depakene (PO) | Key Side Effects: drowsiness, weight gain, tremor, hair loss, thrombocytopenia. US Boxed Warnings: may cause fatal hepatic failure; may cause life-threatening pancreatitis; fetal toxicity. |
| Topiramate/ Topamax (PO) | Key Side Effects: somnolence, dizziness, diplopia, ataxia, memory impairment, weight loss |
| Levetiracetam/ Keppra (PO, IV) | Key Side Effects: somnolence, dizziness, diplopia, nausea, vomiting, ataxia, weakness |
| Oxcarbazepine/ Trileptal (PO) | Key Side Effects: somnolence, dizziness, diplopia, nausea, vomiting, ataxia, weakness, hyponatremia |
| Phenobarbital/----(PO, IM, IV) | Key Side Effects: somnolence, dizziness, risk of SJS |
| Phenytoin/ Dilantin (PO, IV) | Key Side Effects: somnolence, dizziness, gingival hyperplasia, hirsutism, risk of SJS. US Boxed Warning: cardiovascular risk with rapid infusion Other Notes: narrow therapeutic index drug (toxicity may occur at concentrations close to therapeutic range; therapeutic drug monitoring is recommended). |
| Gabapentin/ Neurontin (PO) | Key Side Effects: somnolence, dizziness, ataxia, fatigue, diplopia, xerostomia, blurry vision. |
| Pregabalin/ Lyrica (PO) | Key Side Effects: somnolence, dizziness, ataxia, fatigue, diplopia, xerostomia, blurry vision. |