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Anticoag

DrugClassA/E (Besides Bleeding)Considerations
Heparin enhances antithrombin Heparin induced thrombocytopenia (HIT) Ok for preggy aPTT (60-80)
Daletparin LMW Hep
Fondaparinux LMW Hep
Warfarin Inhibits Vit K factors(VII, IX, X) Inhibits prothrombin cascade Fetal hemmorhage/teratogenesis Antidote:Vitamin K no aspirin/acetaminophen no preggy
Dabigatran etexilate Direct thrombin inhibitor GI Watch kidneys -Doesnt require much monitoring and carries low risk of A/E
Rivaroxaban Direct factor Xa inhib inactivation of fibrinogen to fibrin spinal/epidural hematoma with paralysis is possible not preggy safe can impair excretion
Clopidogrel Antiplatelet aggregation similar to aspirin (GI bleeds, etc)
Plasugrel sim to clopidogrel
Ticagrelor sim to clopidogrel
Eptifibatide Antiplatelet Super high risk for bleeding monitor bleeding
Tirofiban Antiplatelet SUper high risk for bleeding monitor bleeding
Created by: tapolk
Popular Pharmacology sets

 

 



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