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Endocrine2
Endocrine2 Essential Knowledge
| Generic/Brand | |
|---|---|
| Drospirenone & Ethinyl Estradiol/ Yasmin, Yaz (PO) | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache. US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke. Other Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer, and cardiovascular disease. |
| Levonorgestrel & Ethinyl Estradiol/ Lutera, Levora, Seasonique (PO) | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache. US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke. Other Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer, and cardiovascular disease. |
| Norethindrone & Ethinyl Estradiol/ Junel, Loestrin, Microgestin (PO) | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache. US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke. Other Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer, and cardiovascular disease. |
| Norethindrone, Ethinyl Estradiol, & Ferrous Fumarate/ Lo Loestrin Fe, Microgestin Fe (PO) | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache. US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke. Other Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer, and cardiovascular disease. |
| Norgestimate & Ethinyl Estradiol/ Ortho Tri-Cyclen Lo, Tri-Sprintec, Sprintec (PO) | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache. US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke. Other Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer, and cardiovascular disease. |
| Norgestrel & Ethinyl Estradiol/ Crysell-28, Low-Ogestrel (PO) | Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache. US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke. Other Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer, and cardiovascular disease. |
| Estrogens, conjugated (equine)/ Premarin (PO, Topical) | KSE irritation at app site (transderm patch only) abdominal pain, breast tenderness, thromboembolic disorders (myocardial infarction, stroke, VTE) US Warn: increased risk of breast cancer; shouldn't be used for dementia prevention; increased risk of endometrial cancer if not used concomitantly with progestin in women with a uterus; shouldn't be used for prevention of cardio disease Other Notes: CI in hepatic dysfunction, thromboembolic disorders, cardio disease, breast cancer & estrogen dependent tumor. |
| Estradiol/ Vivelle Dot, Estrace (Transdermal, PO) | KSE irritation at app site (transderm patch only) abdominal pain, breast tenderness, thromboembolic disorders (myocardial infarction, stroke, VTE) US Warn: increased risk of breast cancer; shouldn't be used for dementia prevention; increased risk of endometrial cancer if not used concomitantly with progestin in women with a uterus; shouldn't be used for prevention of cardio disease Other Notes: CI in hepatic dysfunction, thromboembolic disorders, cardio disease, breast cancer & estrogen dependent tumor. |
| Medroxyprogesterone/ Provera (PO) | Key Side Effects: acne, abnormal menstrual bleeding, headache, amenorrhea. US Boxed Warnings: increased risk of breast cancer; should not be used for dementia prevention; should not be used for prevention of cardiovascular disease. Other Notes: CI in thromboembolic disorders, cardiovascular disease, estrogen or progesterone-dependent tumors, undiagnosed abnormal genital bleeding, hepatic impairment. |