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Cardio4
Cardio4 Essential Knowledge
| Question | Answer |
|---|---|
| Amiodarone/ Pacerone, Nexterone (PO, IV) | Key Side Effects: hypothyroidism, hyperthyroidism, pulmonary toxicity, hepatotoxicity. US Boxed Warnings: life-threatening arrhythmias, pulmonary toxicity, hepatotoxicity. Other Notes: many drug interactions |
| Digoxin/ Digitek, Digox, Lanoxin (PO, IV) | Key Side Effects: nausea, vomiting, visual changes. Other Notes: narrow therapeutic index drug (toxicity may occur at concentrations close to therapeutic range; therapeutic drug monitoring is recommended); signs of toxicity include nausea, vomiting and visual changes; many drug interactions. |
| Ezetimibe/ Zetia (PO) | Key Side Effects: diarrhea |
| Fenofibrate/ Tricor, Trilipix (PO) | Key Side Effects: dyspepsia, myopathy/rhabdomyolysis, elevated hepatic transaminases |
| Gemfibrozil/ Lopid (PO) | Key Side Effects: dyspepsia, myopathy/rhabdomyolysis, elevated hepatic transaminases |
| Atorvastatin/ Lipitor (PO) | Key Side Effects: myopathy/rhabdomyolysis. Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding. |
| Lovastatin/ Mevacor (PO) | Key Side Effects: myopathy/rhabdomyolysis. Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding. |
| Pravastatin/ Pravachol (PO) | Key Side Effects: myopathy/rhabdomyolysis. Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding. |
| Rosuvastatin/ Crestor (PO) | Key Side Effects: myopathy/rhabdomyolysis. Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding. |
| Simvastatin/ Zocor (PO) | Key Side Effects: myopathy/rhabdomyolysis. Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding. |
| Omega-3 fatty acids/ Lovaza, Vascepa (PO) | Key Side Effects: diarrhea, nausea, dysgeusia, eructation |
| Niacin ER/ Niaspan (PO) | Key Side Effects: flushing, pruritus |