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Pralidoxime
EMT Pharm Review
| Term | Definition |
|---|---|
| trade name | 2 PAM Chloride |
| medication class | Cholinesterase re-activator (anticholinesterase antidote) |
| Pharmacologic action | Reactivates cholinesterase, restoring the body’s ability to metabolize acetylcholine |
| indications for administration | Nerve agent exposure |
| contraindications | None when indicated |
| Medication interactions | None |
| adult and pediatric doses | Adult: 600mg; IM, via autoinjector Must be administered via an autoinjector ▪ Nerve Agent Antidote Kit (NAAK) • Mark 1 kit • Duodose repeat every 3 - 5 mins until desired effect ; same for PED |
| Special notes | Will not work for pesticides of the carbamate class. ✓Must be given in conjunction with Atropine (Duodose) or after Atropine (Mark I kit) |