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Naloxone

EMT Pharm Review

TermDefinition
trade name narcan
medication class opioid antagonist
Pharmacologic action Briefly and competitively antagonizes opioid receptors blocking opioid effects.
indications for administration Treatment of known opiate/opioid overdose Unconscious for unknown reason, but has decreased respiratory rate (suspicion of opiate/opioid use)
contraindications Absence of indications
Medication interactions Administration of naloxone can result in the sudden onset of withdrawal (agitation, tachycardia, pulmonary edema, nausea, vomiting, and, in neonates, seizures)
adult and pediatric doses Patient over age 5 and/or 20kg: 0.4-2mg; IM/ 2mg; IN (1mg per nare) Patient under age 5 and/or 20kg: o 0.1mg/kg IM Repeat every 3-5 mins MCEP after 2 mg is needed
special notes Patient may quickly become conscious and combative; with large doses (greater than 4-5mg) flash pulmonary edema has been encountered. Doses higher than 2mg are often necessary for patients under the influence of opioids with longer transports
Created by: jovanroman
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