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pharm exam 3
Question | Answer |
---|---|
Adrenergic vs Cholinergic | 18 The autonomic nervous system is yet further subdivided into parasympathetic (cholinergic) and sympathetic (adrenergic). |
Conditions that are contraindications for beta blocker administration. | uncompensated heart failure, cardiogenic shock, heart block or bradycardia, pregnancy, severe pulmonary disease, and Raynaud's disease. All beta blockers share a black box warning stating that therapy should not be withdrawn abruptly but should be taper |
Carvedilol | It is used primarily in the treatment of heart failure but is also beneficial for hypertension and angina. |
Labetalol | It is used in the treatment of severe hypertension and hypertensive emergencies to quickly lower the blood pressure before permanent damage is done. |
Metoprolol | Studies have shown increased survival in patients given the drug after they have experienced an MI. |
Propranolol (also contraindicated with what condition?) | In addition to the indications mentioned for metoprolol, propranolol has been used for the treatment of tachydysrhythmias associated with cardiac glycoside intoxication and for the treatment of hypertrophic subaortic stenosis, pheochromocytoma, thyrotoxic |
Pilocarpine | 19 used as a miotic in the treatment of glaucoma. |
Tolterodine | 19 used for the treatment of urinary frequency, urgency, and urge incontinence caused by bladder (detrusor) overactivity |
Anticholinergics prior to surgery | Transdermal scopolamine may be applied preoperatively to help prevent postoperative postanesthesia nausea/vomiting with application 1 hour before surgery and removed within 24 to 36 hours. |
Scopolamine transdermal | Transdermal scopolamine may be applied preoperatively to help prevent postoperative postanesthesia nausea/vomiting with application 1 hour before surgery and removal within 24 to 36 hours. Transdermal scopolamine may cause drowsiness, dry mouth, and blurr |
Atropine | it is used to treat bradycardia and ventricular asystole. |
Atropine is used as an antidote for anticholinesterase inhibitor toxicity or poisoning. | It is also used preoperatively to reduce salivation and GI secretions, as is glycopyrrolate. Atropine is contraindicated in patients with angle-closure glaucoma, and it should be used with caution in patients with advanced hepatic and renal dysfunction |
Patient teaching for monitoring while taking beta blockers | it is used to treat bradycardia and ventricular asystole. Atropine is used as an antidote for anticholinesterase inhibitor toxicity or poisoning. It is also used preoperatively to reduce salivation and GI secretions, as is glycopyrrolate. Atropine is cont |
Drug classes that interact with beta blockers | bottom |
Alpha blocker side effect | first dose phynominon, orthostatic hypotension, palpiatations, tachycardia, edema, chestpain, dizziness, h/a, anxiety, depression, weakness, numbess, fatigue, N/V/D, constipation, abdominal pain. Alpha blocker fi |
Sign of increasing gastrointestinal motility | 19 increased gastric secretions, GI motility, and urinary frequency. |
Donepezil indications & teaching | 20 It is used in the treatment of mild to moderate Alzheimer's disease. |
Cevimeline therapeutic effect | treat excessively dry mouth (xerostomia) resulting from a disorder known as Sjögren's syndrome |
Edrophonium is given to aid in the diagnosis of: | used to diagnose myasthenia gravis. It can also be used to differentiate between myasthenia gravis and cholinergic crisis. |
Atropine adverse effect | 21 coma, tachycardia, dry mouth, polyuria, swelling of eyes |
Atropine overdose assessment | 19 ransient syncope, transient complete heart block, dyspnea, and orthostatic hypotension may also occur. These can be reversed promptly by the administration of atropine, a cholinergic antagonist |
Patient teaching with atropine administration | subcut/im/iv 30-60 min before anestesia |
Risks for elderly taking anticholinergics | The older adult patient is extremely sensitive to the central nervous system (CNS) effects of anticholinergics, and it is not uncommon for delirium to develop because of anticholinergic effects. |
Desired effect of cholinergic blocking eyedrops | 21 anticholinergics cause the pupils to dilate and increase intraocular pressure |
Inotropic | 18 Positive inotropic effect An increase in the force of contraction of the heart muscle (myocardium). |
Chronotropic | 18 Positive chronotropic effect An increase in heart rate. |
Dromotropic | 18 Positive dromotropic effect An increase in the conduction of cardiac electrical impulses through the atrioventricular node, which results in the transfer of nerve action potentials from the atria to the ventricles. This ultimately leads to a systolic h |
Epinephrine actions | It is considered the prototypical nonselective adrenergic agonist. At low dosages, it stimulates mostly beta1-adrenergic receptors, increasing the force of contraction and heart rate. It is also used to treat acute asthma (see Chapter 37) and anaphy |
Adverse effect of beta blockers | bradycardia, depression, impotence, constipation, and fatigue. Some of the most serious undesirable effects can be caused by acute withdrawal of the drug. For example, such sudden withdrawal may exacerbate underlying angina, precipitate an MI, or cause |
Why would a beta blocker be given to a patient after an MI? | 19 When a beta blocker occupies myocardial beta1 receptors, circulating catecholamine molecules are prevented from binding to the receptors. Thus the beta blockers protect the heart from being stimulated by these catecholamines. Because of this characteri |
Teaching for client taking tamsulosin | 19 1. do not disco abruptly. 2. do not use OTC w/o HPC. 3. may cause dizzy at first. 4. take 30 min after meal. Priapism may occur. 5. do not crush caps. |