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Drugs Set 1
| Question | Answer |
|---|---|
| What is the presentation of Adrenaline? 1 | 1mg in 1ml Amp (1:1000) |
| What is the presentation of Adrenaline? 2 | 1mg in 10ml Amp (1:10000) |
| What is the Pharmacology Description of Adrenaline? | A naturally occurring Alpha and Beta-adrenergic stimulant |
| What is the Pharmacology Action of Adrenaline? 1 | Increases pulse rate by increasing S.A. Node firing rate (Beta 1) |
| What is the Pharmacology Action of Adrenaline? 2 | Increases conduction velocity through the A.V. Node (Beta 1) |
| What is the Pharmacology Action of Adrenaline? 3 | Increases myocardial contractility (Beta 1) |
| What is the Pharmacology Action of Adrenaline? 4 | Increases the irritability of the ventricles (Beta 1) |
| What is the Pharmacology Action of Adrenaline? 5 | Causes bronchodilatation (Beta 2) |
| What is the Pharmacology Action of Adrenaline? 6 | Causes peripheral vasoconstriction (Alpha) |
| How is Adrenaline Metabolised? | By monoamine oxidase and other enzymes in blood, liver and around nerve endings and excreted by the kidneys |
| What are the Primary Emergency Indications of Adrenaline? 1 | Persistent ventricular fibrillation or unconscious pulseless ventricular tachycardia |
| What are the Primary Emergency Indications of Adrenaline? 2 | Asystole |
| What are the Primary Emergency Indications of Adrenaline? 3 | Electro‑mechanical dissociation/PEA |
| What are the Primary Emergency Indications of Adrenaline? 4 | Inadequate perfusion (Cardiogenic) |
| What are the Primary Emergency Indications of Adrenaline? 5 | Inadequate Perfusion (Non Cardiogenic – Non Hypovolaemic) |
| What are the Primary Emergency Indications of Adrenaline? 6 | Anaphylactic reactions |
| What are the Primary Emergency Indications of Adrenaline? 7 | Severe asthma |
| What are the Primary Emergency Indications of Adrenaline? 8 | Unconscious asthma with no blood pressure |
| What are the Primary Emergency Indications of Adrenaline? 9 | Croup or suspected croup |
| What are the Primary Emergency Indications of Adrenaline? 10 | Bradycardia with poor perfusion |
| What is the contraindication of Adrenaline? | Hypovolaemic shock without adequate fluid replacement |
| What are the precautions associated with Adrenaline? 1 | Elderly Pts |
| What are the precautions associated with Adrenaline? 2 | Pts with cardiovascular disease |
| What are the precautions associated with Adrenaline? 3 | Pts on monoamine oxidase (MAO) inhibitors |
| What are the precautions associated with Adrenaline? 4 | Pts on Beta blockers as higher doses may be required |
| What is a route of administration of Adrenaline? 1 | Intravenous |
| What is a route of administration of Adrenaline? 2 | Intramuscular |
| What is a route of administration of Adrenaline? 3 | Endotracheal |
| What is a route of administration of Adrenaline? 4 | Nebuliser |
| What is a route of administration of Adrenaline? 5 | Intravenous Infusion |
| What is a route of administration of Adrenaline? 6 | Intraosseous |
| What are the side effects of Adrenaline? 1 | Sinus tachycardia |
| What are the side effects of Adrenaline? 2 | Supraventricular arrhythmias |
| What are the side effects of Adrenaline? 3 | Ventricular arrhythmias |
| What are the side effects of Adrenaline? 4 | Hypertension |
| What are the side effects of Adrenaline? 5 | Pupillary dilatation |
| What are the side effects of Adrenaline? 6 | May increase size of myocardial infarction |
| What are the side effects of Adrenaline? 7 | Feeling of “anxiety/palpitations” in the conscious Pt |
| Special Notes Adrenaline - General | Intravenous Adrenaline should be reserved for life threatening situations. |
| Special Notes Adrenaline - Intravenous effects Onset | 30sec |
| Special Notes Adrenaline - Intravenous effects Peak | 3 – 5min |
| Special Notes Adrenaline - Intravenous effects Duration | 5 – 10min. |
| Special Notes Adrenaline - Intramuscular effects Onset | 30 – 90sec |
| Special Notes Adrenaline - Intramuscular effects Peak | 4 – 10min |
| Special Notes Adrenaline - Intramuscular effects Duration | 5 – 10min |