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Module 13
Section 7: Drug-disease interactions
Question | Answer |
---|---|
Three health conditions that affect medications | Kidney disease Liver disease Heart failure |
Characteristics of medications that are most affected by li9ver disease | Medications with high volumes of distribution that are highly bound to plasma proteins |
Characteristics of medications that are most affected by kidney disease. | Medications with low volumes f distribution and low plasma protein binding |
Which measure of kidney function is the basis of many dosing regiments in patients with kidney disease? | Creatinine clearance |
Which liver enzymes are used to test liver function when determining dosage regimens? | ALT AST Alkaline phosphatase |
What is hear failure? | The inability of the heart to pump blood effciently |
What is a common result of heart failure? | Edema, or pooling of fluid in the ankles |
Effect of taking oral corticosteroids in patients with heart failure | Increased sodium and water retention, contributing to fluid overload and edema |
Effect of taking metformin in patients with heart failure | Increased risk of lactic acidosis |
Effect of taking calcium channel blockers such as diltiazem and verapamil in patients with heart failure. | Decreased cardiac conduction. |