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Module 13

Section 7: Drug-disease interactions

QuestionAnswer
Three health conditions that affect medications Kidney disease Liver disease Heart failure
Characteristics of medications that are most affected by li9ver disease Medications with high volumes of distribution that are highly bound to plasma proteins
Characteristics of medications that are most affected by kidney disease. Medications with low volumes f distribution and low plasma protein binding
Which measure of kidney function is the basis of many dosing regiments in patients with kidney disease? Creatinine clearance
Which liver enzymes are used to test liver function when determining dosage regimens? ALT AST Alkaline phosphatase
What is hear failure? The inability of the heart to pump blood effciently
What is a common result of heart failure? Edema, or pooling of fluid in the ankles
Effect of taking oral corticosteroids in patients with heart failure Increased sodium and water retention, contributing to fluid overload and edema
Effect of taking metformin in patients with heart failure Increased risk of lactic acidosis
Effect of taking calcium channel blockers such as diltiazem and verapamil in patients with heart failure. Decreased cardiac conduction.
Created by: Lane.Wendy
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