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General Terminology

Pharmacy 200

QuestionAnswer
absorption the process of absorbing or of being absorbed
addiction compulsive physiological need for and use of a habit-forming substance characterized by tolerance and by well-defined physiological symptoms upon withdrawal
agonist a chemical substance (as a drug) capable of combining with a receptor on a cell and initiating the same reaction or activity typically produced by the binding of an endogenous substance
antagonist a chemical that acts within the body to reduce the physiological activity of another chemical substance (as an opiate)
blood-brain barrier a naturally occurring barrier created by the modification of brain capillaries that prevents many substances from leaving the blood and crossing the capillary walls into the brain tissues
brand name
chemical name
class name
distribution the pattern of branching and termination of a ramifying anatomical structure (as a nerve or artery)
dose the measured quantity of a therapeutic agent to be taken at one time
dose response relationship the change in effect on an organism caused by differing levels of exposure (or doses) to a stressor (usually a chemical) after a certain exposure time
ED50 Median effective dose
efficacy the maximum response achievable from a drug
elimination clearance of a drug or other foreign agent from the body
generic name The official nonproprietary name of a drug, under which it is licensed and identified by the manufacturer
half life the time that a living body requires to eliminate one half the quantity of an administered substance (as a radioisotope) through its normal channels of elimination
LD50 value Lethal Dose; The dose of a chemical or biological preparation that is likely to cause death.
maximum effect
metabolism the chemical changes in living cells by which energy is provided for vital processes and activities and new material is assimilated
pathophysiology the functional changes that accompany a particular syndrome or disease
pharmacodynamics a branch of pharmacology dealing with the reactions between drugs and living systems
pharmacokinetics the characteristic interactions of a drug and the body in terms of its absorption, distribution, metabolism, and excretion
pharmacology the science of drugs including their origin, composition, pharmacokinetics, therapeutic use, and toxicology
placebo a usually pharmacologically inert preparation prescribed more for the mental relief of the patient than for its actual effect on a disorder
potency chemical or medicinal strength or efficacy <a drug's potency>
receptor a cellular entity (as a beta-receptor or alpha-receptor) that is a postulated intermediary between a chemical agent (as a neurohormone) acting on nervous tissue and the physiological or pharmacological response
sensitization the process of becoming sensitive or hypersensitive (as to an antigen)
therapeautic index a measure of the relative desirability of a drug for the attaining of a particular medical end that is usually expressed as the ratio of the largest dose producing no toxic symptoms to the smallest dose routinely producing cures
therapeautics a branch of medical science dealing with the application of remedies to diseases <cancer therapeutics>
tolerance the capacity of the body to endure or become less responsive to a substance (as a drug) or a physiological insult especially with repeated use or exposure <developed a tolerance to painkillers>
toxicology a science that deals with poisons and their effect and with the problems involved (as clinical, industrial, or legal)
Created by: dkaur
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