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Pharm T3 Breakdown

QuestionAnswer
Diluent Fluid that makes mixture less concentrated. Fluid dilutes mixture. Used to convert dry substance to liquid.
Reconstitution Combining dry mixture with fluid
Solution Concentration (Strength) Amt of drug in quantity of solution expressed as ratio, fraction, or %. EX. 100mg/100mL or 1:1 EX. 1/2 strength or 50% solution
Suspension Liquid where fine particles are dispersed throughout fluid by shaken or stirred. If left alone, solid particles settle. EX. Antibiotics are often oral suspensions
Bolus Concentrated med solution given by IV over brief time. Often by IV push (direct inj into vein)
Continuous IV infusion IV sol that flows continuously and doesn't have a stop or discontinue date/time. Pts that're NPO or surgical usually get Cont IV infusion. EX. Dextrose 5% in water at 75mL/hr.
Drop Factor (DF or Tubing Factor) # of gtt per mL through IV tubing. Tubing diameter affects size of drop. Used to calculate flow rates on gravity devices.
Flow Rate Rate which fld is delivered by IV infusion devices, usually in whole mL/hr. EX. Infuse [sol] at 100ml/hr.
Primary Infusion Line Main IV line connected to Pt. May have 1+ primary line. First line is usually "dedicated" to fluid delivery, maintenance. Addtl lines reserved for meds or medicated solutions that're incompatible with other fluids.
Secondary Infusion Line Tubing that connects to ports on primary line. Permits variety of addtl meds/flds to be added w/o disruption of primary line.
Intermittent Infusions Small-vol medicated IV sol delivered at intervals. IVPB equip, syringe pumps, calibrated volume-control burette chambers are most common.
IVPB Small-vol infusions (50-100mL) infused through short secondary tubing line that's PB to port on primary line. Intermittent medicated infusions are delivered over 20-60min.
IV Push (incorrectly addreviated as IVP) IV concentrated, medicated, intermittent bolus dose of 1-50mL, usually administered by manual direct inj c syringe, sometimes via infusion pump.
Macrodrip Gravity IV infusion tubing set that has wide diameter to deliver large drops, fast flow rates (10-20 gtt/mL DF)
Microdrip Gravity IV infusion tubing set that has narrow diameter to deliver small drops, slow flow rates (60 gtt/mL DF)
PCA pump Pt-controlled analgesia pump by remote push button. Programmed to dispense prescribed amts of analgesic narcotics & other meds at prescribed intermittent intervals c intermittent lockout intervals.
TKO/KVO To Keep Open/Keep Vein Open. Flow rate order for min rate that will keep the IV line patent and prevent coagulation.
DM Endocrine disorder affecting pancreatic insulin production. utilization, & carb, fat, P metabolism. Characterized by high blood glucose levels.
DM Type I Little or no insulin production by beta cells. Usual onset in childhood. Treated with insulin hormone administration.
DM Type II Some insulin production but not enough or resistance to insulin utilization. Controlled c dietary/lifestyle changes or treated c oral antidiabetics. Insulin may be added.
DKA (Diabetic Ketoacidosis) Emergency condition diagnosed by high blood glucose levels (>250mg/dL), blood pH <7.3, elevated ketones in blood and urine, and often coma. Requires hospitalization and insulin therapy.
Glucagon Blood glucose-raising hormone secreted by alpha cells. Released in response to fall below normal blood glucose levels.
Insulin Blood glucose-lowering hormone produced by beta cells in pancreas. Starts entry of glucose into muscle cells for E storage. Lowers blood glucose levels. (INsulin helps glucose get IN to cells)
Hyperglycemia Elevated glucose level in blood
Hypoblycemia Decreased glucose level in blood
Insulin Resistance Decreased tissue ability to respond to insulin. Glucose level rises. Hyperinsulinemia occurs. Occurs in Type II, obese, HTN Pts.
Insulin Shock Blood glucose <60mg/dL. Cause by OD of insulin or taking insulin and eating at wrong time.
Units Measurement of therapeutic effectiveness.
Blood Glucose (BG) BG test.
Fasting Blood Sugar (FBS) Fasting 8-12hr shows current blood glucose level
Fructosamine Determines avg blood glucose level over past 2 wks
Glycosylated Hemoglobin (A1c or HbA1c) Determines avg blood glucose lever over past 2-3 mo. Measures amt of glucose attached to hemoglobin in RBC.
Postprandial Glucose Test 2h pc blood glucose test. Results are elevated in diabetics.
Normal level of Fasting Blood Glucose level 70-100 mg/dL
Reconstituted meds can be used ONLY: If the reconstituted med is appropriately labeled: Pt's name. Date/time of prep. Diluent type. Amt added. Concentration per mL p dilution. Nurse's sig. Discard date/time.
Parenteral meds are Sterile or Non-Sterile? Sterile
Diluent for reconstitution of parenteral meds are Sterile or Non-Sterile? Sterile
Adult avg IM inj is X mL? No more than 3 mL
You should select a dilution that permits at least X mL of IM inj. 0.5 mL
Orders can be written in 3 ways to indicate the strength or concentration of a solution. %, Fraction, Ratio
Concentrate Med needs to be diluted
Inactive Diluents NS, SW, Bacteriostatic Saline
Dilute In In Addition To (Add enough diluent to make total)
Dilute To Total (subtract the med amt from the total amt = how much diluent is needed)
Macrodrip tubing has a DF of: 10, 15, or 20 gtt/mL (DF10, DF15, DF20)
Microdrip tubing has a DF of: 60 gtt/mL (DF60)
D stands for Dextrose
L/R stands for lactated Ringer's
When do you use microdrip tubing? With peds and blood or more viscous meds
One calculation needed for all infusion rates? Determination of # of mL/hr
Flow rates of mL/hr and gtt/min are rounded: To nearest whole #
On gravity dependent devices, the Primary or Secondary flows first? Whichever one is higher
If answer is >60 gtt/min then: Recheck answer bc it's probably wrong
mL/hr and gtt/min will be = if using DF of? DF60 bc there are 60min in an hour
Which renal function tests should you know about when dealing with Potassium? BUN, Creatinine, and K level
You should never administer K: Undiluted
What can undiluted K cause? Tissue necrosis, vessel damage, and cardiac arrest
Hypokalemia Too little K
Hyperkalemia Too much K
S/S of Hypokalemia Small elevation of blood pressure. Cardiac arrythmia. Muscular weakness. Myalgia. Muscle cramps. Constipation. Flaccid paralysis. Hyporeflexia. Tetany.
S/S of Hyperkalemia Malaise. Palpitations. Muscle weakness. Mild hyperventilation. Cardiac arrhythmia. Death
Insulin is given by what route? SQ
What insulins can be given by IV? Humulin R and Lispro (Humalog)
Intermediate and Long acting insulins should be ____ before drawing up. Gently rolled (Cloudy is rolled, clear isn't)
Lantus and Levemir insulins are both short, intermediate, or long acting? Long acting insulin
Which insulins do not have a peak? Lantus and Levemir
Which insulins can't be mixed with other insulins? Lantus and Levemir
Which insulins should be given at the same time q day? Lantus and Levemir
Can insulins come premixed? Yes, Novolog Mix 70/30. Humalog Mix 75/25. Novolin 70/30. Humulin 70/30. Humulin 50/50.
Should you roll or shake insulins that are premixed? Yes.
Insulin IV infusions are usually mixed with concentrations of ___unit/mL or ___unit/mL 0.5 unit/mL or 1 unit/mL
What is regular or short acting insulin normally mixed with? NS
What type of insulin do insulin pumps contain? Short or regular insulin
What basal rate are short acting (regular) insulin given at in insulin pumps? Slow continuous basal rate
What Pts are insulin pumps normally used for? Diabetics with blood sugar that's difficult to control.
Created by: mcwilliams05
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