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Module 13

Section 1: Pharmacodynamics

QuestionAnswer
What is pharmacodynamics? A subset of pharmacology that deals with how medications cause their effects on the body
Three concepts addressed in pharmacodynamics The medication's mechanism of action (agonist or antagonist) Therapeutic window Therapeutic index
Example of an agonist Albuterol stimulates bronchiole dilation to help patients with asthma breathe better.
Example of an antagonist Metoprolol inhibits the stimulation of the heart to decrease cardiac output
What is an agonist? A medication that stimulates the effects of an existing process
What does a wide therapeutic window indicate? A medication with a greater range of doses that will work for patieints.
How is the therapeutic index (TI) value determined? By taking the toxic dose of a given medication and dividing by the effective dose.
What does a high therapeutic index (TI) value indicate? Medications with a higher TI are safer.
Examples of medication with a high therapeutic index ibuprofen
Example of medication with a low therapeutic index Phenytoin
Created by: Lane.Wendy
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