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Anti-Infective 2
3 anti infective medications for pharm
| Term | Definition |
|---|---|
| Fluconazole | of 5 different classes, an anti fungal used for secondary infections caused by other antibiotics. |
| Fluconazole Uses | Candidasis and Histoplasmosis (infection caused by breathing in fungus) |
| Fluconazole Teachings | Take as directed and suspension refrigerate |
| Fluconazole Nursing Actions | Monitor renal/Hepatic function, PT/INR |
| Fluconazole Side Effects | GI upset, |
| Fluconazole Adverse Reactions | TEN, Hepatotoxicity (liver damage) |
| Fluconazole Interactions | Caffeine |
| Hydroxychloroquine | is an Antimalarial |
| Malaria -travel bug | The most prevalent protozoan disease; carried by mosquitoes and has become resistant to treatment |
| Hydroxychloroquine Uses | Malaria and Malaria prophylaxis |
| Hydroxychloroquine Teachings | Routine eye exams. Take on an empty stomach. BEHAVIORAL DISTURBANCES |
| Hydroxychloroquine Nursing Actions | Monitor EKG and Liver function test. and suicidal ideations (Hold and have an evaluation) |
| Hydroxychloroquine Side Effects | Pruritis |
| Hydroxychloroquine Adverse Reactions | Arrythmias, TEN |
| Hydroxychloroquine interactions | Digoxin, neuromuscular blockers |
| Hydroxychloroquine Contraindications | Cardiac disease and Ocular disease, psoriasis |
| Metronidazole | a nitromidazole that disrupts DNA synthesis in susceptible bacteria and protozoa |
| Metronidazole Uses | C. Diff. Trichinosis. BV. Acne Rosacea. Surgical Prophylaxis |
| Metronidazole Teachings | Metallic Taste. Take with food or milk. |
| Metronidazole Nursing Actions | Monitor Weakness. Intake and Output |
| Metronidazole Side Effects | Dry Mouth. Urine Discoloration |
| Metronidazole Adverse Reactions | SJS. TEN. |
| Metronidazole Interactions | Milk thistle |
| Metronidazole Contraindications | Pregnancy. Breastfeeding. Alcohol (DLR) |
| Adult Immunizations | Tetanus, MMR, Varicella, Pneumococcal, Hep A, Hep B, Seasonal FLU, Meningococcal, Herpes Zoster |
| T dap | 10 years and up booster |
| D Tap | Less than 10 years |
| MMR | Live Vaccine. Can't give to pregnant women. Ask for pregnancy test |
| Varicella | Live Vaccine. Can't give to pregnant women. Ask for pregnancy test |
| Things to know when giving a vaccine | pg. 401 Date. Route. Site. Type of vaccine. Manufacturers. Lot #. Expiration. Location of clinic. Name and title of person giving the vaccine. |
| Mild Reaction | Low grade fever. Swelling at the injection site. |
| Immunization Contraindications | Moderate-severe acute illness. History of anaphylaxis. History of reaction to vaccine or vaccine component. Immunocompromised |
| Tetanus is adm. | IM |
| MMR is adm. | SC |
| Pneumococcal is adm. | IM, SC |
| Varicella is adm. | SC |
| Hep A is adm. | IM |
| Hep B is adm. | IM |
| Influenza is adm. | IM, ID, IN |
| Meningococcal is adm. | SC, IM |
| Herpes Zoster is adm. | SC |
| Fluconazole can cause | Hypokalemia |
| Early signs of Hypokalemia | Fatigue. Muscle weakness. Anorexia. Nausea. Vomiting. |
| Severe S&S of hypokalemia | Paresthesia. Leg Cramps. Decreased Bowel Motility. Confusion. Rhabdomyolysis |
| Signs and Symptoms of Malaria | Abdominal cramps. Pruritis. Visual Changes. Dizziness. NVD. |
| 3 types of immunity | Active. Passive. Community |
| Active Immunity | Exposed than antigen/pathogen. Body develops antibodies. Occurs naturally (exposure) or actively (vaccine. Slowly and lasts longer |
| Passive Immunity | The body can not form a response, so immunity is passed from antibodies (inactivated vaccines) |
| Community Immunity (Heard Immunity) | Most of the community is immunized which protects the unimmunized (COVID for ex.) |
| Types of Vaccines | Inactive. Attenuated. Toxoids. Conjugate. Recombinant sub-unit. Adjuvant. mRNA |
| Inactive | Killed microorganism |
| Attenuated | Live, weakened microorganisms. Immunocompromised patients shouldn't get these |
| Toxoids | Inactivated toxins can no longer produce harm but do stimulate formation of anti-toxins (tetanus) |
| Conjugate | New vaccine that require a protein or toxoid from another organism to link to produce an immune response. (h.flu B for infants) |
| Recombinant sub-unit | include some genetic material (DNA) of a pathogen which stimulates antibody production. These antibodies are then used as the vaccine (hep B) |
| Adjuvant | Added to a vaccine to improve the bodies response. Usually aluminum salts. |
| mRNA | Vaccines are now being used. These teach the cell to make a protein that triggers an immune response, similar to conjugate or sub-unit. These are quicker to produce because the others require a human protein. |
| Where is IM given? | Deltoid for adults (shoulder) |
| Where is Sub Q (SC) given? | In either the outer aspect of the upper arm or anterolateral thigh. (NO ABDOMEN) |